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- W4285131738 abstract "Up to 80% patients who present with pancreatic ductal adenocarcinoma (PDAC) are not suitable for surgical resection, a treatment that provides the best survival outcome for these patients [1, 2]. A significant proportion of these patients have locally invasive diseases that are classified as “borderline resectable” or “locally advanced” diseases [3]. Neoadjuvant chemotherapy, either FOLFIRINOX or Gemcitabine-Nabpaclitaxel, has been the gold-standard treatment for these patients as it can result in the downstaging of cancer and enable margin-free resection (termed conversion surgery) in approximately 25% of patients [4]. The addition of targeted radiotherapy, in the form of stereotactic body radiotherapy (SBRT), to chemotherapy, has been shown to increase the rate of conversion surgery by up to 60% for the “borderline resectable” and 40% for the “locally advanced” PDAC [5], providing support for the use of combined chemo-radiotherapy for unresectable PDAC." @default.
- W4285131738 created "2022-07-14" @default.
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- W4285131738 date "2022-01-01" @default.
- W4285131738 modified "2023-09-29" @default.
- W4285131738 title "EUS-Guided Implantation of Radioactive Phosphorus (32P) for Locally Advanced Pancreatic Cancer" @default.
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- W4285131738 doi "https://doi.org/10.1007/978-981-16-9340-3_46" @default.
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