Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285153606> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4285153606 endingPage "51" @default.
- W4285153606 startingPage "43" @default.
- W4285153606 abstract "Introduction: Each year, about 15 million babies are born preterm, and 1 million babies die due to complications of preterm birth. Antenatal corticosteroid is one of the most effective evidence-based interventions that can reduce mortality and morbidity in preterm newborns. Objective: The purpose of this study was to evaluate the effect of antenatal corticosteroids on respiratory morbidities and neurodevelopmental outcomes among preterm neonates. Methodology: This prospective cohort study included admitted premature infant’s ≤ 34 weeks. Infant’s baseline demographics and maternal history of complete ACS exposure or no exposure were evaluated. Development of respiratory morbidities with support was compared between two groups during the neonatal period. After discharge from the NICU, neonates were followed up to assess neurodevelopment at 3rd and 6th months of age using Bayley Scales of Infant Development (BSID-III). Analysis was done to see the relationship with ACS exposure. Results: A total of 82 neonates were enrolled. Among them, 44 neonates in the ACS exposed group and 38 in the ACS unexposed group were assessed for the development of respiratory morbidity. Only 9(20.5%) in the ACS exposed group and 28 (73.7%) in the ACS unexposed group developed respiratory morbidities. Respiratory support with duration was also needed more in the ACS unexposed group.Neurodevelopmental assessment at 3 months was significantly lower in all three domains between the ACS exposed and unexposed groups: cognition (81.67±7.58 vs. 73.50±10.16: p-<0.001). motor (84.50±9.83 vs. 76.83±12.03, p-0.013) and language (84.67±6.33 vs.77.88±9.98, p-0.004) respectively. At 6 months, motor and language scores improved, though cognition was low in both groups. In univariate analysis, ACS exposure was found to be a significant factor in relation to normal neurodevelopment. Conclusion: Antenatal corticosteroid therapy effectively reduces respiratory morbidities in preterm neonates born ≤ 34 weeks of gestation. ACS exposure was also associated with improved neurodevelopmental outcome." @default.
- W4285153606 created "2022-07-14" @default.
- W4285153606 creator A5000929309 @default.
- W4285153606 creator A5001532090 @default.
- W4285153606 creator A5003580968 @default.
- W4285153606 creator A5008004233 @default.
- W4285153606 creator A5008150251 @default.
- W4285153606 creator A5030095522 @default.
- W4285153606 creator A5030238195 @default.
- W4285153606 creator A5086126140 @default.
- W4285153606 creator A5086839698 @default.
- W4285153606 date "2022-01-01" @default.
- W4285153606 modified "2023-09-24" @default.
- W4285153606 title "Respiratory Morbidities and Neurodevelopmental Outcome in Preterm Infants of Mother Exposed to Antenatal Corticosteroids" @default.
- W4285153606 doi "https://doi.org/10.31782/ijcrr.2022.141308" @default.
- W4285153606 hasPublicationYear "2022" @default.
- W4285153606 type Work @default.
- W4285153606 citedByCount "0" @default.
- W4285153606 crossrefType "journal-article" @default.
- W4285153606 hasAuthorship W4285153606A5000929309 @default.
- W4285153606 hasAuthorship W4285153606A5001532090 @default.
- W4285153606 hasAuthorship W4285153606A5003580968 @default.
- W4285153606 hasAuthorship W4285153606A5008004233 @default.
- W4285153606 hasAuthorship W4285153606A5008150251 @default.
- W4285153606 hasAuthorship W4285153606A5030095522 @default.
- W4285153606 hasAuthorship W4285153606A5030238195 @default.
- W4285153606 hasAuthorship W4285153606A5086126140 @default.
- W4285153606 hasAuthorship W4285153606A5086839698 @default.
- W4285153606 hasBestOaLocation W42851536061 @default.
- W4285153606 hasConcept C103728769 @default.
- W4285153606 hasConcept C118552586 @default.
- W4285153606 hasConcept C126322002 @default.
- W4285153606 hasConcept C164953862 @default.
- W4285153606 hasConcept C169900460 @default.
- W4285153606 hasConcept C187212893 @default.
- W4285153606 hasConcept C188816634 @default.
- W4285153606 hasConcept C201903717 @default.
- W4285153606 hasConcept C2778376644 @default.
- W4285153606 hasConcept C2778721537 @default.
- W4285153606 hasConcept C2779234561 @default.
- W4285153606 hasConcept C534529494 @default.
- W4285153606 hasConcept C54355233 @default.
- W4285153606 hasConcept C71924100 @default.
- W4285153606 hasConcept C72563966 @default.
- W4285153606 hasConcept C86803240 @default.
- W4285153606 hasConceptScore W4285153606C103728769 @default.
- W4285153606 hasConceptScore W4285153606C118552586 @default.
- W4285153606 hasConceptScore W4285153606C126322002 @default.
- W4285153606 hasConceptScore W4285153606C164953862 @default.
- W4285153606 hasConceptScore W4285153606C169900460 @default.
- W4285153606 hasConceptScore W4285153606C187212893 @default.
- W4285153606 hasConceptScore W4285153606C188816634 @default.
- W4285153606 hasConceptScore W4285153606C201903717 @default.
- W4285153606 hasConceptScore W4285153606C2778376644 @default.
- W4285153606 hasConceptScore W4285153606C2778721537 @default.
- W4285153606 hasConceptScore W4285153606C2779234561 @default.
- W4285153606 hasConceptScore W4285153606C534529494 @default.
- W4285153606 hasConceptScore W4285153606C54355233 @default.
- W4285153606 hasConceptScore W4285153606C71924100 @default.
- W4285153606 hasConceptScore W4285153606C72563966 @default.
- W4285153606 hasConceptScore W4285153606C86803240 @default.
- W4285153606 hasIssue "13" @default.
- W4285153606 hasLocation W42851536061 @default.
- W4285153606 hasOpenAccess W4285153606 @default.
- W4285153606 hasPrimaryLocation W42851536061 @default.
- W4285153606 hasRelatedWork W2135421145 @default.
- W4285153606 hasRelatedWork W2317865103 @default.
- W4285153606 hasRelatedWork W2340068406 @default.
- W4285153606 hasRelatedWork W2908918753 @default.
- W4285153606 hasRelatedWork W2917993456 @default.
- W4285153606 hasRelatedWork W2955122765 @default.
- W4285153606 hasRelatedWork W3029423869 @default.
- W4285153606 hasRelatedWork W4220664808 @default.
- W4285153606 hasRelatedWork W4313027405 @default.
- W4285153606 hasRelatedWork W4382618506 @default.
- W4285153606 hasVolume "14" @default.
- W4285153606 isParatext "false" @default.
- W4285153606 isRetracted "false" @default.
- W4285153606 workType "article" @default.