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- W4285157104 abstract "Occupational, accidental, diagnostic, or therapeutic exposure to ionizing radiation (IR) in today’s world is inevitable. Radiation, a known mutagen, can also impart transgenerational effects and lead to life-threatening diseases like cancer, cardiovascular, diabetes, or neurological disorders. Recently, epigenetic effects of radiation exposure are being elaborately studied worldwide. DNA methylation and histone modifications (acetylation, methylation, phosphorylation, and sumoylation)-led chromatin remodeling and subsequent alterations in gene expression pattern are being studied more explicitly in various pathophysiological or stress conditions. Epidrugs can modulate the epigenetic aberrations caused due to radiation or other stress exposure. In this chapter, alteration in epigenome due to radiation exposure and the diseases conditions associated will be discussed along with their possible modification by epidrugs to improve life conditions for postradiotherapy patients." @default.
- W4285157104 created "2022-07-14" @default.
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- W4285157104 date "2022-01-01" @default.
- W4285157104 modified "2023-09-28" @default.
- W4285157104 title "Radiation-Induced Epigenetic Changes And Their Modulation By Epidrugs" @default.
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- W4285157104 doi "https://doi.org/10.1007/978-981-16-1247-3_84-2" @default.
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