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• W4285255739 abstract "Infectious diseases have blazed a trail across the globe like a wildfire and are among the leading causes of death. Especially among low- and middle-income countries (LMIC), respiratory infections, tuberculosis, malaria, and HIV/AIDS account for the top contributing factors of death [8]. With the lack of proper medical care and distribution of drugs in these areas, the treatment of infectious diseases is arduous. There is a need for large scale and cheap production of effective therapeutic agents to combat the deadly effect of pathogens. The usage of drugs often provides more harm than good due to the current mechanism resulting in delivery to uninfected areas of the body, cytotoxicity, and shorter duration of therapy. Nanotechnology is a growing area of research, and its applications in providing alternative mechanisms for treating infectious diseases are displaying promising results. Specifically, polymeric nanomaterials offer a solution to achieve targeted delivery of drugs and vaccines. The nanoscale sizes and versatility of particles provide enhanced biodegradability, controlled release, and capability for delivering hydrophobic and hydrophilic drugs through nontraditional administration in epithelial surfaces to avoid contamination are the potential benefits polymeric nanomaterials provide [11]. Additionally, polymeric nanomaterials composed of natural polymers such as chitosan, albumin, and alginate are easier to obtain and cheaper to utilize, thus attributing to the greater cost efficiency aspect [6]. These methods could also result in decreased demands for frequent doses of medication, which simplify treatment in LMIC. The following sections aim to analyze the application of various polymeric nanomaterials, such as poly(lactic-co-glycolic acid) and hydrogels in the most detrimental infectious diseases, ranging from pulmonary to diarrheal pathogens. Application of nanotechnology towards treatment and preventive measures are shown to be predominantly positive, with data revealing up to a 99% efficacy for the several infectious diseases covered in this chapter." @default.
• W4285255739 created "2022-07-14" @default.
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• W4285255739 date "2022-01-01" @default.
• W4285255739 modified "2023-10-16" @default.
• W4285255739 title "Polymeric nanomaterials for infectious diseases" @default.
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• W4285255739 doi "https://doi.org/10.1016/b978-0-323-91201-3.00007-4" @default.
• W4285255739 hasPublicationYear "2022" @default.
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