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- W4285256979 abstract "Cereals comprise an indispensable part of the human diet. However, their production encounters various limitations, including reduced farming areas and low yield and productivity mainly due to abiotic and biotic stress factors. Abiotic stresses such as drought, salinity, extreme temperatures, anoxia/hypoxia, and heavy metal toxicity contribute to the limiting crop productivity worldwide. With a rocketing increase in the human population, challenges to accomplish the demand for food security amidst the adverse effects of climate changes are of paramount importance. In this regard, technological advancements in plant breeding and genetic engineering approaches to improve abiotic stress tolerance are the call of the hour. With the introduction of genome editing technologies like meganucleases, zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR-Cas), precise and efficient double-strand break (DSB) in the targeted gene sequences aids in manipulating the genome. Successful genome editing to overcome/mitigate various abiotic stresses has been demonstrated in major cereal crops such as rice, maize, and wheat but remains unexplored in barley, sorghum, and millets. Genome editing (GE) technologies including the much-acclaimed “CRISPR/Cas” are the most promising options for precise engineering of desired genes into cereal crops with enhanced tolerance to single or multiple abiotic stresses. This chapter highlights the recent advancements, challenges, and prospects of GE and CRISPR-Cas technologies in mitigation of abiotic stresses in cereals. It also sheds light on the potential of GE technologies to be exploited for crops like barley, sorghum, and millets." @default.
- W4285256979 created "2022-07-14" @default.
- W4285256979 creator A5040520059 @default.
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- W4285256979 creator A5053319077 @default.
- W4285256979 creator A5064615580 @default.
- W4285256979 creator A5068591688 @default.
- W4285256979 date "2022-01-01" @default.
- W4285256979 modified "2023-10-16" @default.
- W4285256979 title "Genome Editing and CRISPR-Cas Technology for Enhancing Abiotic Stress Tolerance in Cereals" @default.
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