Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285263273> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4285263273 endingPage "82" @default.
- W4285263273 startingPage "77" @default.
- W4285263273 abstract "Objective. To assess effect of topical use of solution containing ferrous ions on efficacy of metronidazole therapy in women with recurrent urogenital trichomoniasis. Materials and Methods. The study enrolled 55 women aged of 20–30 years with recurrent trichomoniasis after failures of multiple standard of care regimens. All patients received oral (tablets) and intravaginal (1% gel) metronidazole therapy. Participants in the experimental group (29 women) received intravaginal therapy with a solution of ferrous ions at concentration which was determined as effective for potentiating metronidazole in a previous study. In the control group, saline solution was used. Biological samples for laboratory tests were collected prior to treatment and on treatment days 4, 8 and 22. Treatment efficacy was assessed by laboratory results (detection of T. vaginalis, leukocyte-epithelial index). Results. Concomitant use of solutions containing ferrous ions at concentration 8.96 mmol/L can increase frequency of successful treatment outcomes in recurrent trichomoniasis. T. vaginalis was detected at the end of therapy in 10.3% of patients from the experimental group and 69.2% of patients from the control group. Conclusions. The concomitant use of metronidazole and solution containing ferrous ions makes it possible to increase the efficacy of therapy for Trichomonas infection. The results of the study allow us to consider topical use of iron-containing drugs to increase metronidazole treatment efficacy in recurrent trichomoniasis." @default.
- W4285263273 created "2022-07-14" @default.
- W4285263273 creator A5001479068 @default.
- W4285263273 creator A5068882627 @default.
- W4285263273 creator A5074596611 @default.
- W4285263273 creator A5092311777 @default.
- W4285263273 date "2022-01-01" @default.
- W4285263273 modified "2023-09-26" @default.
- W4285263273 title "Effect of topical use of solution containing ferrous ions on treatment efficacy in women with recurrent urogenital trichomoniasis" @default.
- W4285263273 cites W1966227767 @default.
- W4285263273 cites W1970506827 @default.
- W4285263273 cites W1975755011 @default.
- W4285263273 cites W1984915593 @default.
- W4285263273 cites W1995659918 @default.
- W4285263273 cites W1999503251 @default.
- W4285263273 cites W2011224335 @default.
- W4285263273 cites W2016867367 @default.
- W4285263273 cites W2055567790 @default.
- W4285263273 cites W2063982991 @default.
- W4285263273 cites W2110080186 @default.
- W4285263273 cites W2124029883 @default.
- W4285263273 cites W2137094186 @default.
- W4285263273 cites W2142085746 @default.
- W4285263273 cites W2164924374 @default.
- W4285263273 cites W2258841189 @default.
- W4285263273 cites W2566765866 @default.
- W4285263273 cites W2774745237 @default.
- W4285263273 cites W2801727384 @default.
- W4285263273 cites W2963541510 @default.
- W4285263273 cites W3046690023 @default.
- W4285263273 doi "https://doi.org/10.36488/cmac.2022.1.77-82" @default.
- W4285263273 hasPublicationYear "2022" @default.
- W4285263273 type Work @default.
- W4285263273 citedByCount "0" @default.
- W4285263273 crossrefType "journal-article" @default.
- W4285263273 hasAuthorship W4285263273A5001479068 @default.
- W4285263273 hasAuthorship W4285263273A5068882627 @default.
- W4285263273 hasAuthorship W4285263273A5074596611 @default.
- W4285263273 hasAuthorship W4285263273A5092311777 @default.
- W4285263273 hasBestOaLocation W42852632731 @default.
- W4285263273 hasConcept C126322002 @default.
- W4285263273 hasConcept C133507102 @default.
- W4285263273 hasConcept C178790620 @default.
- W4285263273 hasConcept C185592680 @default.
- W4285263273 hasConcept C2775832776 @default.
- W4285263273 hasConcept C2777023796 @default.
- W4285263273 hasConcept C2777396551 @default.
- W4285263273 hasConcept C2779384505 @default.
- W4285263273 hasConcept C2781114625 @default.
- W4285263273 hasConcept C29456083 @default.
- W4285263273 hasConcept C501593827 @default.
- W4285263273 hasConcept C71924100 @default.
- W4285263273 hasConcept C86803240 @default.
- W4285263273 hasConcept C89423630 @default.
- W4285263273 hasConcept C90924648 @default.
- W4285263273 hasConceptScore W4285263273C126322002 @default.
- W4285263273 hasConceptScore W4285263273C133507102 @default.
- W4285263273 hasConceptScore W4285263273C178790620 @default.
- W4285263273 hasConceptScore W4285263273C185592680 @default.
- W4285263273 hasConceptScore W4285263273C2775832776 @default.
- W4285263273 hasConceptScore W4285263273C2777023796 @default.
- W4285263273 hasConceptScore W4285263273C2777396551 @default.
- W4285263273 hasConceptScore W4285263273C2779384505 @default.
- W4285263273 hasConceptScore W4285263273C2781114625 @default.
- W4285263273 hasConceptScore W4285263273C29456083 @default.
- W4285263273 hasConceptScore W4285263273C501593827 @default.
- W4285263273 hasConceptScore W4285263273C71924100 @default.
- W4285263273 hasConceptScore W4285263273C86803240 @default.
- W4285263273 hasConceptScore W4285263273C89423630 @default.
- W4285263273 hasConceptScore W4285263273C90924648 @default.
- W4285263273 hasLocation W42852632731 @default.
- W4285263273 hasOpenAccess W4285263273 @default.
- W4285263273 hasPrimaryLocation W42852632731 @default.
- W4285263273 hasRelatedWork W2055064558 @default.
- W4285263273 hasRelatedWork W2085275785 @default.
- W4285263273 hasRelatedWork W2097304393 @default.
- W4285263273 hasRelatedWork W2114708620 @default.
- W4285263273 hasRelatedWork W2410572362 @default.
- W4285263273 hasRelatedWork W2426317783 @default.
- W4285263273 hasRelatedWork W3082103702 @default.
- W4285263273 hasRelatedWork W3160847307 @default.
- W4285263273 hasRelatedWork W4285263273 @default.
- W4285263273 hasRelatedWork W48437301 @default.
- W4285263273 isParatext "false" @default.
- W4285263273 isRetracted "false" @default.
- W4285263273 workType "article" @default.