Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285280043> ?p ?o ?g. }
- W4285280043 endingPage "117727192211051" @default.
- W4285280043 startingPage "117727192211051" @default.
- W4285280043 abstract "Traumatic brain injury (TBI) is not a single disease state but describes an array of conditions associated with insult or injury to the brain. While some individuals with TBI recover within a few days or months, others present with persistent symptoms that can cause disability, neuropsychological trauma, and even death. Understanding, diagnosing, and treating TBI is extremely complex for many reasons, including the variable biomechanics of head impact, differences in severity and location of injury, and individual patient characteristics. Because of these confounding factors, the development of reliable diagnostics and targeted treatments for brain injury remains elusive. We argue that the development of effective diagnostic and therapeutic strategies for TBI requires a deep understanding of human neurophysiology at the molecular level and that the framework of multiomics may provide some effective solutions for the diagnosis and treatment of this challenging condition. To this end, we present here a comprehensive review of TBI biomarker candidates from across the multiomic disciplines and compare them with known signatures associated with other neuropsychological conditions, including Alzheimer's disease and Parkinson's disease. We believe that this integrated view will facilitate a deeper understanding of the pathophysiology of TBI and its potential links to other neurological diseases." @default.
- W4285280043 created "2022-07-14" @default.
- W4285280043 creator A5035608941 @default.
- W4285280043 creator A5039257128 @default.
- W4285280043 creator A5052805690 @default.
- W4285280043 creator A5080202389 @default.
- W4285280043 creator A5087743116 @default.
- W4285280043 date "2022-01-01" @default.
- W4285280043 modified "2023-09-30" @default.
- W4285280043 title "Progress Toward a Multiomic Understanding of Traumatic Brain Injury: A Review" @default.
- W4285280043 cites W1164825681 @default.
- W4285280043 cites W1484298026 @default.
- W4285280043 cites W1505106692 @default.
- W4285280043 cites W1522996100 @default.
- W4285280043 cites W1572490995 @default.
- W4285280043 cites W1582020170 @default.
- W4285280043 cites W1603121691 @default.
- W4285280043 cites W1703133408 @default.
- W4285280043 cites W1761787460 @default.
- W4285280043 cites W1805451181 @default.
- W4285280043 cites W1831894188 @default.
- W4285280043 cites W1847168837 @default.
- W4285280043 cites W1879457624 @default.
- W4285280043 cites W1881234275 @default.
- W4285280043 cites W1883979382 @default.
- W4285280043 cites W1912691389 @default.
- W4285280043 cites W1963790961 @default.
- W4285280043 cites W1968007289 @default.
- W4285280043 cites W1968854054 @default.
- W4285280043 cites W1968900405 @default.
- W4285280043 cites W1969069107 @default.
- W4285280043 cites W1969086552 @default.
- W4285280043 cites W1969416735 @default.
- W4285280043 cites W1971448332 @default.
- W4285280043 cites W1973633053 @default.
- W4285280043 cites W1974151084 @default.
- W4285280043 cites W1974561853 @default.
- W4285280043 cites W1977263445 @default.
- W4285280043 cites W1977819986 @default.
- W4285280043 cites W1981082943 @default.
- W4285280043 cites W1981247845 @default.
- W4285280043 cites W1981509058 @default.
- W4285280043 cites W1982051443 @default.
- W4285280043 cites W1984596349 @default.
- W4285280043 cites W1986702986 @default.
- W4285280043 cites W1989265845 @default.
- W4285280043 cites W1989963651 @default.
- W4285280043 cites W1991893128 @default.
- W4285280043 cites W1997921895 @default.
- W4285280043 cites W1998817080 @default.
- W4285280043 cites W1999173521 @default.
- W4285280043 cites W2000209446 @default.
- W4285280043 cites W2000581338 @default.
- W4285280043 cites W2003923114 @default.
- W4285280043 cites W2004631917 @default.
- W4285280043 cites W2005560590 @default.
- W4285280043 cites W2007453010 @default.
- W4285280043 cites W2007986677 @default.
- W4285280043 cites W2008854521 @default.
- W4285280043 cites W2009178440 @default.
- W4285280043 cites W2009330906 @default.
- W4285280043 cites W2009412756 @default.
- W4285280043 cites W2011595299 @default.
- W4285280043 cites W2012503195 @default.
- W4285280043 cites W2013583419 @default.
- W4285280043 cites W2013700204 @default.
- W4285280043 cites W2013813451 @default.
- W4285280043 cites W2014252830 @default.
- W4285280043 cites W2014578307 @default.
- W4285280043 cites W2015466408 @default.
- W4285280043 cites W2022621268 @default.
- W4285280043 cites W2023819682 @default.
- W4285280043 cites W2025302671 @default.
- W4285280043 cites W2025745896 @default.
- W4285280043 cites W2028265367 @default.
- W4285280043 cites W2033552121 @default.
- W4285280043 cites W2036974074 @default.
- W4285280043 cites W2037425720 @default.
- W4285280043 cites W2042085520 @default.
- W4285280043 cites W2042990492 @default.
- W4285280043 cites W2044038782 @default.
- W4285280043 cites W2047108031 @default.
- W4285280043 cites W2048130772 @default.
- W4285280043 cites W2049864513 @default.
- W4285280043 cites W2050322930 @default.
- W4285280043 cites W2050800676 @default.
- W4285280043 cites W2054105805 @default.
- W4285280043 cites W2054376401 @default.
- W4285280043 cites W2054395884 @default.
- W4285280043 cites W2054683575 @default.
- W4285280043 cites W2058035812 @default.
- W4285280043 cites W2058161128 @default.
- W4285280043 cites W2058381071 @default.
- W4285280043 cites W2060348280 @default.
- W4285280043 cites W2062179679 @default.
- W4285280043 cites W2062993238 @default.
- W4285280043 cites W2065167286 @default.
- W4285280043 cites W2067975546 @default.