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- W4285289976 abstract "According to statistics, cardiovascular disease accounts for 17.7 million deaths worldwide each year. In recent years, radiation therapy or radiotherapy (RT) has become an important method of treating tumors, especially in the multimodal treatment of thoracic cancer. In addition to improving survival rates of tumor patients, radiation exposure also causes some inevitable complications. Radiation-induced heart disease (RIHD) has become increasingly recognized as an adverse event that contributes to nonmalignant death among radiation-associated toxicities due to significant improvements in overall cancer survival. Patients suffering from diseases with excellent prognosis such as breast cancer or Hodgkin’s lymphoma will be at greater risk of developing RIHD since RIHD may occur decades after radiotherapy. Major cardiovascular events are more likely to occur in individuals who have coexisting metabolic syndrome and preexisting atherosclerosis as well as exposure to RT. In order to devise optimal prevention and surveillance strategies, it is important to understand the underlying pathophysiology and clinical manifestations of RT-induced cardiovascular disease. In this chapter, the biological mechanisms of RIHD, the available treatment options, and the challenges in treating it are summarized." @default.
- W4285289976 created "2022-07-14" @default.
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- W4285289976 date "2022-01-01" @default.
- W4285289976 modified "2023-10-16" @default.
- W4285289976 title "Cardiovascular risk induced by radiotherapy" @default.
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- W4285289976 doi "https://doi.org/10.1016/b978-0-323-90461-2.00014-6" @default.
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