Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285292013> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4285292013 abstract "Purpose: To investigate the protective effect of penehyclidine hydrochloride (PHC) on cardiopulmonary bypass (CPB)-related lung injury in rats. Methods: Thirty-six rats were divided into control, CPB and PHC groups. The CPB model was established in CPB and PHC groups. In PHC group, 2-mg/kg PHC was added to the pre-filling solution for CPB modeling. At 30 min before CPB (T1), immediately after left hilar opening (T2) and end of experiment (T3), the hemodynamic indexes, blood gas indexes, serum inflammatory factors, lung wet-day ratio and water content and lung tissue oxidative stress indexes were determined. Results: At T2 and T3, compared with CPB group, in PHC group the heart rate and mean arterial pressure increased significantly, the oxygenation index increased significantly, the respiratory index decreased significantly, and the lung wet-day ratio and water content decreased significantly. At T3, compared with CPB group, in PHC groups the serum tumor necrosis factor α, interleukin 6 and interleukin 1β levels decreased significantly, the lung tissue superoxide dismutase level increased significantly, and the myeloperoxidase and malondialdehyde levels decreased significantly. Conclusions: PHC treatment can alleviate the CPB-related lung injury in rats. The mechanisms may be related to its reducing inflammatory response and resisting oxidative stress." @default.
- W4285292013 created "2022-07-14" @default.
- W4285292013 creator A5000228481 @default.
- W4285292013 creator A5002848069 @default.
- W4285292013 creator A5047886994 @default.
- W4285292013 creator A5059471140 @default.
- W4285292013 creator A5091459844 @default.
- W4285292013 date "2022-01-01" @default.
- W4285292013 modified "2023-10-01" @default.
- W4285292013 title "Effect of penehyclidine hydrochloride on inflammatory response and oxidative stress in rats with cardiopulmonary bypass related-lung injury" @default.
- W4285292013 cites W1559100610 @default.
- W4285292013 cites W1966328848 @default.
- W4285292013 cites W2010045015 @default.
- W4285292013 cites W2050087783 @default.
- W4285292013 cites W2052128294 @default.
- W4285292013 cites W2053889157 @default.
- W4285292013 cites W2083278380 @default.
- W4285292013 cites W2109324622 @default.
- W4285292013 cites W2142875831 @default.
- W4285292013 cites W2301725624 @default.
- W4285292013 cites W2744892122 @default.
- W4285292013 cites W2782959446 @default.
- W4285292013 cites W2806817136 @default.
- W4285292013 cites W2821468664 @default.
- W4285292013 cites W2913647872 @default.
- W4285292013 cites W2921386164 @default.
- W4285292013 cites W2945900515 @default.
- W4285292013 cites W3088990303 @default.
- W4285292013 cites W3093168285 @default.
- W4285292013 cites W3116009753 @default.
- W4285292013 cites W3144399358 @default.
- W4285292013 cites W3163603143 @default.
- W4285292013 doi "https://doi.org/10.1590/acb370406" @default.
- W4285292013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35766672" @default.
- W4285292013 hasPublicationYear "2022" @default.
- W4285292013 type Work @default.
- W4285292013 citedByCount "0" @default.
- W4285292013 crossrefType "journal-article" @default.
- W4285292013 hasAuthorship W4285292013A5000228481 @default.
- W4285292013 hasAuthorship W4285292013A5002848069 @default.
- W4285292013 hasAuthorship W4285292013A5047886994 @default.
- W4285292013 hasAuthorship W4285292013A5059471140 @default.
- W4285292013 hasAuthorship W4285292013A5091459844 @default.
- W4285292013 hasBestOaLocation W42852920131 @default.
- W4285292013 hasConcept C126322002 @default.
- W4285292013 hasConcept C203565725 @default.
- W4285292013 hasConcept C2775838275 @default.
- W4285292013 hasConcept C2776151105 @default.
- W4285292013 hasConcept C2776914184 @default.
- W4285292013 hasConcept C2777714996 @default.
- W4285292013 hasConcept C2778401633 @default.
- W4285292013 hasConcept C2778881276 @default.
- W4285292013 hasConcept C2780826366 @default.
- W4285292013 hasConcept C42219234 @default.
- W4285292013 hasConcept C70289976 @default.
- W4285292013 hasConcept C71924100 @default.
- W4285292013 hasConceptScore W4285292013C126322002 @default.
- W4285292013 hasConceptScore W4285292013C203565725 @default.
- W4285292013 hasConceptScore W4285292013C2775838275 @default.
- W4285292013 hasConceptScore W4285292013C2776151105 @default.
- W4285292013 hasConceptScore W4285292013C2776914184 @default.
- W4285292013 hasConceptScore W4285292013C2777714996 @default.
- W4285292013 hasConceptScore W4285292013C2778401633 @default.
- W4285292013 hasConceptScore W4285292013C2778881276 @default.
- W4285292013 hasConceptScore W4285292013C2780826366 @default.
- W4285292013 hasConceptScore W4285292013C42219234 @default.
- W4285292013 hasConceptScore W4285292013C70289976 @default.
- W4285292013 hasConceptScore W4285292013C71924100 @default.
- W4285292013 hasIssue "4" @default.
- W4285292013 hasLocation W42852920131 @default.
- W4285292013 hasLocation W42852920132 @default.
- W4285292013 hasLocation W42852920133 @default.
- W4285292013 hasOpenAccess W4285292013 @default.
- W4285292013 hasPrimaryLocation W42852920131 @default.
- W4285292013 hasRelatedWork W1990447376 @default.
- W4285292013 hasRelatedWork W2041257525 @default.
- W4285292013 hasRelatedWork W2106072534 @default.
- W4285292013 hasRelatedWork W2183540883 @default.
- W4285292013 hasRelatedWork W2352692432 @default.
- W4285292013 hasRelatedWork W2360386157 @default.
- W4285292013 hasRelatedWork W2509589047 @default.
- W4285292013 hasRelatedWork W4281566553 @default.
- W4285292013 hasRelatedWork W4303437387 @default.
- W4285292013 hasRelatedWork W4365802299 @default.
- W4285292013 hasVolume "37" @default.
- W4285292013 isParatext "false" @default.
- W4285292013 isRetracted "false" @default.
- W4285292013 workType "article" @default.