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- W4285296880 endingPage "171" @default.
- W4285296880 startingPage "129" @default.
- W4285296880 abstract "Viruses can be considered as one of the most common causes of human disease. The human immunodeficiency virus (HIV) causing acquired immunodeficiency syndrome (AIDS) in humans appeared about 40 years ago and is still a major global health problem. On the other hand, during all this time there has been great progress in antiretroviral treatment, which has significantly prolonged and improved the quality of life of HIV-positive patients and AIDS patients. In addition to the design of new drugs and various types of antibodies and vaccines, reformulations of the existing drugs are applied to modern drug delivery nanosystems that enable fixed-dose drug combinations and modified administration, dosing, release, and targeting. In addition to oral nanosystems, alternative forms of administration, such as implants, patches, and vaginal preparations, are increasingly being used. It is important to note that a number of other natural or inorganic compounds have been shown to be effective against HIV in the nanoform. In this context, it is also necessary to mention the increasing attention paid to HIV preexposure prophylaxis. This chapter provides a comprehensive up-to-date overview of different types of ARV nanoformulations of drugs, including delivery nanosystems with fixed-dose drug combinations. In addition, various other nanoscale agents active against HIV are discussed. The basic classification and life cycle of viruses, their role in natural systems, and the impact on immune defense are briefly mentioned for the sake of clarity as well." @default.
- W4285296880 created "2022-07-14" @default.
- W4285296880 creator A5043344521 @default.
- W4285296880 creator A5082502261 @default.
- W4285296880 date "2022-01-01" @default.
- W4285296880 modified "2023-10-16" @default.
- W4285296880 title "Nanotechnology: New frontiers in anti-HIV therapy" @default.
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