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- W4285296961 abstract "B cell-mediated pathologies such as the production of autoantibodies are known to adversely affect pregnancy outcomes. Conversely, maternal production of asymmetric antibodies is often viewed as protective. However, what direct role B cells play in the orchestrated immune adaptations needed to support pregnancy remains under investigation. Here, evidence of the potential role of B cells in normal pregnancy is outlined, with alterations in B cell phenotype and function and links with pregnancy pathologies communicated. Early B cell-mediated treatment options for recurrent pregnancy loss are proposed and discussed in the context of what is known and what remains to be determined to support clinical development." @default.
- W4285296961 created "2022-07-14" @default.
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- W4285296961 date "2022-01-01" @default.
- W4285296961 modified "2023-09-30" @default.
- W4285296961 title "B cell pathology and recurrent pregnancy loss" @default.
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- W4285296961 doi "https://doi.org/10.1016/b978-0-323-90805-4.00016-x" @default.
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