Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285303941> ?p ?o ?g. }
- W4285303941 endingPage "443" @default.
- W4285303941 startingPage "409" @default.
- W4285303941 abstract "Circulating biomarkers are widely used in the management of patients with cancer, especially in assessing prognosis, surveillance following curative-intent surgery and monitoring therapy. Inadequate sensitivity and specificity, however, limit the use of most existing biomarkers in screening asymptomatic subjects for early malignancy. Currently, only two circulating biomarkers are recommended for cancer screening, that is, prostate-specific antigen for prostate cancer following a process of shared decision-making and alpha-fetoprotein in specific high-risk subjects for hepatocellular cancer. Emerging biomarkers include circulating tumor DNA (ctDNA), micro-RNAs, circulating tumor cells, and extracellular vesicles. Of these, ctDNA is likely to have the biggest clinical impact, especially for early cancer detection/screening and therapy planning. Among the currently approved ctDNA biomarkers are mutant EGFR for predicting response to EGFR inhibitors in advanced nonsmall cell lung cancer, mutant PIK3CA for predicting response to alpelisib in combination with fulvestrant in advanced breast cancer and methyl SEPT9 in screening for early colorectal cancer." @default.
- W4285303941 created "2022-07-14" @default.
- W4285303941 creator A5067762018 @default.
- W4285303941 date "2022-01-01" @default.
- W4285303941 modified "2023-09-28" @default.
- W4285303941 title "Circulating cancer biomarkers: current status and future prospects" @default.
- W4285303941 cites W139215267 @default.
- W4285303941 cites W1976194250 @default.
- W4285303941 cites W1997310608 @default.
- W4285303941 cites W2003487510 @default.
- W4285303941 cites W2009775937 @default.
- W4285303941 cites W2011824883 @default.
- W4285303941 cites W2025890159 @default.
- W4285303941 cites W2039507551 @default.
- W4285303941 cites W2069129640 @default.
- W4285303941 cites W2117098158 @default.
- W4285303941 cites W2120357482 @default.
- W4285303941 cites W2127821100 @default.
- W4285303941 cites W2128104740 @default.
- W4285303941 cites W2131181434 @default.
- W4285303941 cites W2139566281 @default.
- W4285303941 cites W2149634277 @default.
- W4285303941 cites W2159007127 @default.
- W4285303941 cites W2166084034 @default.
- W4285303941 cites W2171858932 @default.
- W4285303941 cites W2261070115 @default.
- W4285303941 cites W2316242722 @default.
- W4285303941 cites W2460179076 @default.
- W4285303941 cites W2495997243 @default.
- W4285303941 cites W2547719552 @default.
- W4285303941 cites W2560070768 @default.
- W4285303941 cites W2601644616 @default.
- W4285303941 cites W2623493302 @default.
- W4285303941 cites W2742681205 @default.
- W4285303941 cites W2761031851 @default.
- W4285303941 cites W2765540742 @default.
- W4285303941 cites W2772104639 @default.
- W4285303941 cites W2783375881 @default.
- W4285303941 cites W2783674487 @default.
- W4285303941 cites W2785515282 @default.
- W4285303941 cites W2786099441 @default.
- W4285303941 cites W2787046878 @default.
- W4285303941 cites W2791546899 @default.
- W4285303941 cites W2793326518 @default.
- W4285303941 cites W2800112295 @default.
- W4285303941 cites W2800738672 @default.
- W4285303941 cites W2803442701 @default.
- W4285303941 cites W2811305164 @default.
- W4285303941 cites W2886336921 @default.
- W4285303941 cites W2899540665 @default.
- W4285303941 cites W2900295924 @default.
- W4285303941 cites W2900680116 @default.
- W4285303941 cites W2906447738 @default.
- W4285303941 cites W2907814135 @default.
- W4285303941 cites W2921497169 @default.
- W4285303941 cites W2922490216 @default.
- W4285303941 cites W2937538955 @default.
- W4285303941 cites W2939548416 @default.
- W4285303941 cites W2941797036 @default.
- W4285303941 cites W2945564879 @default.
- W4285303941 cites W2946670461 @default.
- W4285303941 cites W2947989913 @default.
- W4285303941 cites W2966632204 @default.
- W4285303941 cites W2982743561 @default.
- W4285303941 cites W2987712342 @default.
- W4285303941 cites W2988773550 @default.
- W4285303941 cites W2990041408 @default.
- W4285303941 cites W2990870977 @default.
- W4285303941 cites W3003654340 @default.
- W4285303941 cites W3005153366 @default.
- W4285303941 cites W3007391700 @default.
- W4285303941 cites W3009594177 @default.
- W4285303941 cites W3009861434 @default.
- W4285303941 cites W3010470146 @default.
- W4285303941 cites W3010889616 @default.
- W4285303941 cites W3011778928 @default.
- W4285303941 cites W3013146920 @default.
- W4285303941 cites W3013924915 @default.
- W4285303941 cites W3015202523 @default.
- W4285303941 cites W3015227813 @default.
- W4285303941 cites W3015885334 @default.
- W4285303941 cites W3021934789 @default.
- W4285303941 cites W3022151901 @default.
- W4285303941 cites W3022801864 @default.
- W4285303941 cites W3036325293 @default.
- W4285303941 cites W3048572852 @default.
- W4285303941 cites W3048596299 @default.
- W4285303941 cites W3087210493 @default.
- W4285303941 cites W3141884635 @default.
- W4285303941 cites W3164727223 @default.
- W4285303941 cites W4247781752 @default.
- W4285303941 doi "https://doi.org/10.1016/b978-0-12-824302-2.00009-6" @default.
- W4285303941 hasPublicationYear "2022" @default.
- W4285303941 type Work @default.
- W4285303941 citedByCount "0" @default.
- W4285303941 crossrefType "book-chapter" @default.
- W4285303941 hasAuthorship W4285303941A5067762018 @default.
- W4285303941 hasConcept C121608353 @default.