Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285307930> ?p ?o ?g. }
- W4285307930 endingPage "513" @default.
- W4285307930 startingPage "501" @default.
- W4285307930 abstract "Traumatic brain injury is a global public health concern, with limited treatment options available. Despite improving survival rate after TBI, there are currently no effective therapeutic strategies to mitigate the long-term sequelae of TBI. Different pharmacological approaches targeting the pathophysiology of TBI has drawn attention, especially those able to block multiple neurotoxic events following the inciting TBI event. In this way, guanosine, a purinergic nucleoside, has excelled out for its broad neuromodulatory and neurorepair aspects in different experimental models of neurological disorders. The inter-relation between the adenosinergic and glutamatergic systems to maintain the functionality of the central nervous system has been associated with its neuroprotective effects. These cellular pathways have characteristic of maintaining behavioral capacity such as memory, cognition, and attention. Thus, this chapter summarizes pharmacological strategies of guanosine which have been explored in preclinical models of TBI and proposed new perspectives for possible clinical translational studies." @default.
- W4285307930 created "2022-07-14" @default.
- W4285307930 creator A5025453700 @default.
- W4285307930 creator A5025576109 @default.
- W4285307930 creator A5058303296 @default.
- W4285307930 creator A5078831321 @default.
- W4285307930 date "2022-01-01" @default.
- W4285307930 modified "2023-09-27" @default.
- W4285307930 title "Behavioral effects of traumatic brain injury: Use of guanosine" @default.
- W4285307930 cites W1809181152 @default.
- W4285307930 cites W1827056541 @default.
- W4285307930 cites W1971731558 @default.
- W4285307930 cites W1974606313 @default.
- W4285307930 cites W1991376557 @default.
- W4285307930 cites W1992193294 @default.
- W4285307930 cites W1994954159 @default.
- W4285307930 cites W2007957507 @default.
- W4285307930 cites W2012387994 @default.
- W4285307930 cites W2016675737 @default.
- W4285307930 cites W2016789150 @default.
- W4285307930 cites W2021967361 @default.
- W4285307930 cites W2044770790 @default.
- W4285307930 cites W2054048077 @default.
- W4285307930 cites W2059799391 @default.
- W4285307930 cites W2061145676 @default.
- W4285307930 cites W2062497077 @default.
- W4285307930 cites W2072883404 @default.
- W4285307930 cites W2077812845 @default.
- W4285307930 cites W2078379881 @default.
- W4285307930 cites W2081901378 @default.
- W4285307930 cites W2118026709 @default.
- W4285307930 cites W2118965542 @default.
- W4285307930 cites W2119835056 @default.
- W4285307930 cites W2119888580 @default.
- W4285307930 cites W2133164520 @default.
- W4285307930 cites W2135781323 @default.
- W4285307930 cites W2140565326 @default.
- W4285307930 cites W2165040339 @default.
- W4285307930 cites W2189355713 @default.
- W4285307930 cites W2229744007 @default.
- W4285307930 cites W2272566893 @default.
- W4285307930 cites W2307289208 @default.
- W4285307930 cites W2318651009 @default.
- W4285307930 cites W2429063411 @default.
- W4285307930 cites W2472172082 @default.
- W4285307930 cites W2478122494 @default.
- W4285307930 cites W2554805821 @default.
- W4285307930 cites W2560585443 @default.
- W4285307930 cites W2751177312 @default.
- W4285307930 cites W2886598701 @default.
- W4285307930 cites W2901806837 @default.
- W4285307930 cites W2937025324 @default.
- W4285307930 cites W2990737501 @default.
- W4285307930 cites W2995611030 @default.
- W4285307930 cites W3036203198 @default.
- W4285307930 cites W3042787845 @default.
- W4285307930 cites W3049088792 @default.
- W4285307930 cites W3083759682 @default.
- W4285307930 cites W360386621 @default.
- W4285307930 cites W4210979710 @default.
- W4285307930 cites W3043598875 @default.
- W4285307930 doi "https://doi.org/10.1016/b978-0-12-823036-7.00018-9" @default.
- W4285307930 hasPublicationYear "2022" @default.
- W4285307930 type Work @default.
- W4285307930 citedByCount "0" @default.
- W4285307930 crossrefType "book-chapter" @default.
- W4285307930 hasAuthorship W4285307930A5025453700 @default.
- W4285307930 hasAuthorship W4285307930A5025576109 @default.
- W4285307930 hasAuthorship W4285307930A5058303296 @default.
- W4285307930 hasAuthorship W4285307930A5078831321 @default.
- W4285307930 hasConcept C118552586 @default.
- W4285307930 hasConcept C126322002 @default.
- W4285307930 hasConcept C15744967 @default.
- W4285307930 hasConcept C169760540 @default.
- W4285307930 hasConcept C170493617 @default.
- W4285307930 hasConcept C25498285 @default.
- W4285307930 hasConcept C2776992512 @default.
- W4285307930 hasConcept C2778938600 @default.
- W4285307930 hasConcept C2780648746 @default.
- W4285307930 hasConcept C2781017439 @default.
- W4285307930 hasConcept C61174792 @default.
- W4285307930 hasConcept C67907053 @default.
- W4285307930 hasConcept C71924100 @default.
- W4285307930 hasConceptScore W4285307930C118552586 @default.
- W4285307930 hasConceptScore W4285307930C126322002 @default.
- W4285307930 hasConceptScore W4285307930C15744967 @default.
- W4285307930 hasConceptScore W4285307930C169760540 @default.
- W4285307930 hasConceptScore W4285307930C170493617 @default.
- W4285307930 hasConceptScore W4285307930C25498285 @default.
- W4285307930 hasConceptScore W4285307930C2776992512 @default.
- W4285307930 hasConceptScore W4285307930C2778938600 @default.
- W4285307930 hasConceptScore W4285307930C2780648746 @default.
- W4285307930 hasConceptScore W4285307930C2781017439 @default.
- W4285307930 hasConceptScore W4285307930C61174792 @default.
- W4285307930 hasConceptScore W4285307930C67907053 @default.
- W4285307930 hasConceptScore W4285307930C71924100 @default.
- W4285307930 hasLocation W42853079301 @default.
- W4285307930 hasOpenAccess W4285307930 @default.