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• W4285309272 abstract "Cyanobacterial bloom and toxin production are serious environmental and social concerns in freshwater lakes and reservoir all over the world. However, cyanotoxin production from cyanobacteria such as microcystin (MC, known as hepatotoxin) remains inconclusive. To achieve the sustainable management of freshwater bodies, understanding the environmental and physiological factors associated with cyanobacterial toxin generation is important. In this chapter, we focus on the relationship between MC production and metal-induced cellular oxidative stress. First, the results of field surveys in the Tonle Sap Lake and several eutrophic lakes in Japan are introduced as representative examples of cyanobacterial bloom in Asian countries. The concentrations of MC in the Tonle Sap Lake are relatively high, ranging from 8.2 to 70,692 ng/L in the dry season. The water near the Kampong Phluk Port showed the highest MC concentration, whereas the middle of the lake showed lower concentration. Second, laboratory-based culturing experiment using freshwater cyanobacterium Microcystis aeruginosa with varied metal concentrations is introduced, where intracellular MC concentrations are found to be related to the degree of metal-induced oxidative stress. The results suggest that excess heavy metals and nutrient metal deficiency increase oxidative stress and resultant MC generation. Overall, the findings indicate the importance of considering metal concentrations for properly understanding and managing toxic cyanobacterial bloom." @default.
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• W4285309272 date "2022-01-01" @default.
• W4285309272 modified "2023-10-17" @default.
• W4285309272 title "Microcystin Production and Oxidative Stress" @default.
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• W4285309272 doi "https://doi.org/10.1007/978-981-16-6632-2_28" @default.
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