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- W4285331987 abstract "Liposomes are used and heavily researched in drug delivery. These nanocarriers encapsulate therapeutic agents efficiently and deliver their contents to tumors with minimal undesired side effects. In this study, we investigated the preparation of Estrone liposomes in a commercially available microfluidic chip (a Herringbone micromixer). Using this chip, we synthesized Estrone liposomes with high uniformity and reproducibility, contrary to conventional methods (e.g., the thin film hydration), which are cumbersome and non-reliable. In addition, we studied the effect of the lipids concentration and the flow rate ratio between the lipids stream and the aqueous stream on the size and polydispersity of the resulting liposomes. The smallest liposomes obtained were 91.8 ± 4.8nm in radius (mean ± SD) with a polydispersity of 17.2%." @default.
- W4285331987 created "2022-07-14" @default.
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- W4285331987 date "2021-11-15" @default.
- W4285331987 modified "2023-09-27" @default.
- W4285331987 title "Targeted Liposomes Production in a Microfluidic Chip" @default.
- W4285331987 doi "https://doi.org/10.1109/nanomed54179.2021.9766644" @default.
- W4285331987 hasPublicationYear "2021" @default.
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