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- W4285351918 abstract "CieÄžom ĂşÄinnej lieÄby sclerosis multiplex najnovĹĄĂmi preparĂĄtmi je zabrĂĄniĹĽ progredujĂşcej disabilite pacienta. Nenaplnenou potrebou pre dennĂş prax je absencia validnĂ˝ch laboratĂłrnych biomarkerov, ktorĂŠ by nĂĄm okrem zobrazovacĂch metĂłd, ako sĂş magnetickĂĄ rezonancia mozgu a miechy, ukĂĄzali prĂĄve prebiehajĂşcu aktivitu ochorenia u jednotlivĂŠho pacienta a efekt podĂĄvanej lieÄby. Neurofilamenty ÄžahkĂ˝ch reĹĽazcov (NfL) sa povaĹžujĂş za neĹĄpecifickĂ˝ biomarker neurodegenerĂĄcie a dajĂş sa Äžahko vyĹĄetriĹĽ z krvi. V tejto prĂĄci predkladĂĄme prehÄžad vĂ˝sledkov ĹĄtĂşdiĂ hodnotiacich vzĹĽahy hladĂn krvnĂ˝ch NfL k parametrom aktivity ochorenia, zĂĄpalovej aj neurodegeneratĂvnej manifestĂĄcii a odpovedi na lieÄbu." @default.
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- W4285351918 date "2021-10-01" @default.
- W4285351918 modified "2023-10-18" @default.
- W4285351918 title "Neurofilament light chain and disease activity in patients with multiple sclerosis" @default.
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- W4285351918 doi "https://doi.org/10.36290/neu.2021.073" @default.
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