Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285364216> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W4285364216 abstract "Introduction: Diabetes mellitus (DM) is a metabolic disorder appearing as a main public health problem nowadays. Objectives: This study aimed to evaluate the effect of calcitriol on microalbuminuria in patients with type 2 DM (T2DM). Patients and Methods: This double-blind randomized clinical trial was performed on 38 patients with T2DM who had micro- albuminuria. These patients were randomly classified into two groups of treatment and control. The treatment group received calcitriol 0.25 μg daily since the control group received a placebo. Duration of treatment was three months. In baseline, serum creatinine (Cr), fasting blood sugar (FBS), glycated hemoglobin (HbA1c), cholesterol (Chol), triglyceride (TG), low-density lipoprotein (LDL-c), high-density lipoprotein (HDL-c), and micro-albuminuria were measured. Patients were followed up for three months. P<0.05 was set as a significant level. Results: In baseline, two groups did not differ significantly in terms of serum Cr, FBS, HbA1c, Chol, TG, HDL-c, LDL-c, and micro-albuminuria (P> 0.05). After the intervention, there was no significant difference between the two groups regarding the median of serum Cr, FBS, HbA1c, Chol, TG, LDL-c, HDL-c, and microalbuminuria. The median of microalbuminuria in the treatment and control groups was decreased at 46 mg/g and 11 mg/g, respectively. The difference in median of micro-albuminuria was not statically significant between the two groups; however, a significant difference was detected in the treatment group before and after the intervention (P=0.03). Conclusion: Administration of calcitriol could reduce micro-albuminuria after three months. Therefore, the addition of calcitriol to angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) in patients with T2DM and micro- albuminuria may have a beneficial effect on reducing their proteinuria. Trial Registration: The trial protocol was approved by the Iranian Registry of Clinical Trials (identifier: IRCT2016091429812N; https://en.irct.ir/trial/23865, ethical code; IR.SSU.Rec.65415)." @default.
- W4285364216 created "2022-07-14" @default.
- W4285364216 creator A5022026901 @default.
- W4285364216 creator A5029210144 @default.
- W4285364216 creator A5033185796 @default.
- W4285364216 creator A5053449543 @default.
- W4285364216 creator A5075307936 @default.
- W4285364216 date "2021-09-20" @default.
- W4285364216 modified "2023-09-26" @default.
- W4285364216 title "The effects of calcitriol on microalbuminuria in patients with type 2 diabetes mellitus; a double-blind randomized clinical trial" @default.
- W4285364216 doi "https://doi.org/10.34172/jnp.2022.17163" @default.
- W4285364216 hasPublicationYear "2021" @default.
- W4285364216 type Work @default.
- W4285364216 citedByCount "0" @default.
- W4285364216 crossrefType "journal-article" @default.
- W4285364216 hasAuthorship W4285364216A5022026901 @default.
- W4285364216 hasAuthorship W4285364216A5029210144 @default.
- W4285364216 hasAuthorship W4285364216A5033185796 @default.
- W4285364216 hasAuthorship W4285364216A5053449543 @default.
- W4285364216 hasAuthorship W4285364216A5075307936 @default.
- W4285364216 hasBestOaLocation W42853642161 @default.
- W4285364216 hasConcept C124490489 @default.
- W4285364216 hasConcept C126322002 @default.
- W4285364216 hasConcept C126894567 @default.
- W4285364216 hasConcept C134018914 @default.
- W4285364216 hasConcept C142724271 @default.
- W4285364216 hasConcept C204787440 @default.
- W4285364216 hasConcept C27081682 @default.
- W4285364216 hasConcept C2776079296 @default.
- W4285364216 hasConcept C2776174234 @default.
- W4285364216 hasConcept C2777180221 @default.
- W4285364216 hasConcept C2777538456 @default.
- W4285364216 hasConcept C2779561371 @default.
- W4285364216 hasConcept C2780091579 @default.
- W4285364216 hasConcept C2780306776 @default.
- W4285364216 hasConcept C2781203188 @default.
- W4285364216 hasConcept C2910068830 @default.
- W4285364216 hasConcept C555293320 @default.
- W4285364216 hasConcept C71924100 @default.
- W4285364216 hasConcept C90924648 @default.
- W4285364216 hasConceptScore W4285364216C124490489 @default.
- W4285364216 hasConceptScore W4285364216C126322002 @default.
- W4285364216 hasConceptScore W4285364216C126894567 @default.
- W4285364216 hasConceptScore W4285364216C134018914 @default.
- W4285364216 hasConceptScore W4285364216C142724271 @default.
- W4285364216 hasConceptScore W4285364216C204787440 @default.
- W4285364216 hasConceptScore W4285364216C27081682 @default.
- W4285364216 hasConceptScore W4285364216C2776079296 @default.
- W4285364216 hasConceptScore W4285364216C2776174234 @default.
- W4285364216 hasConceptScore W4285364216C2777180221 @default.
- W4285364216 hasConceptScore W4285364216C2777538456 @default.
- W4285364216 hasConceptScore W4285364216C2779561371 @default.
- W4285364216 hasConceptScore W4285364216C2780091579 @default.
- W4285364216 hasConceptScore W4285364216C2780306776 @default.
- W4285364216 hasConceptScore W4285364216C2781203188 @default.
- W4285364216 hasConceptScore W4285364216C2910068830 @default.
- W4285364216 hasConceptScore W4285364216C555293320 @default.
- W4285364216 hasConceptScore W4285364216C71924100 @default.
- W4285364216 hasConceptScore W4285364216C90924648 @default.
- W4285364216 hasLocation W42853642161 @default.
- W4285364216 hasOpenAccess W4285364216 @default.
- W4285364216 hasPrimaryLocation W42853642161 @default.
- W4285364216 hasRelatedWork W1790741237 @default.
- W4285364216 hasRelatedWork W2011841523 @default.
- W4285364216 hasRelatedWork W2163833198 @default.
- W4285364216 hasRelatedWork W2373524078 @default.
- W4285364216 hasRelatedWork W2380217695 @default.
- W4285364216 hasRelatedWork W2435141826 @default.
- W4285364216 hasRelatedWork W3148712325 @default.
- W4285364216 hasRelatedWork W3148745664 @default.
- W4285364216 hasRelatedWork W3155340504 @default.
- W4285364216 hasRelatedWork W4212928020 @default.
- W4285364216 isParatext "false" @default.
- W4285364216 isRetracted "false" @default.
- W4285364216 workType "article" @default.