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• W4285367415 abstract "DNA methylation alterations have been widely studied as mediators of environmentally induced disease risks. With new advances in technique, epigenome-wide DNA methylation data (EWAS) have become the new standard for epigenetic studies in human populations. However, to date most epigenetic studies of mediation effects only involve selected (gene-specific) candidate methylation markers. There is an urgent need for appropriate analytical methods for EWAS mediation analysis. In this chapter, we provide an overview of recent advances on high-dimensional mediation analysis, with application to two DNA methylation data." @default.
• W4285367415 created "2022-07-14" @default.
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• W4285367415 date "2021-09-07" @default.
• W4285367415 modified "2023-10-01" @default.
• W4285367415 title "A Review of High-Dimensional Mediation Analyses in DNA Methylation Studies" @default.
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• W4285367415 doi "https://doi.org/10.1007/978-1-0716-1994-0_10" @default.
• W4285367415 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35505212" @default.
• W4285367415 hasPublicationYear "2021" @default.
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