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- W4285384251 abstract "Chromatin organization is important for many DNA-templated processes in eukaryotic cells such as replication and transcription. Recent studies have uncovered the capacity of epigenetic modifications, phase separation, and nuclear architecture and spatial positioning to regulate chromatin organization in both plants and animals. Here, we provide an overview of the recent progress made in understanding how chromatin is organized within the nucleus at both the local and global levels with respect to the regulation of transcriptional silencing in plants. To be concise while covering important mechanisms across a range of scales, we focus on how epigenetic modifications and chromatin remodelers alter local chromatin structure, how liquid-liquid phase separation physically separates broader chromatin domains into distinct droplets, and how nuclear positioning affects global chromatin organization." @default.
- W4285384251 created "2022-07-14" @default.
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- W4285384251 date "2022-10-01" @default.
- W4285384251 modified "2023-10-18" @default.
- W4285384251 title "Linking transcriptional silencing with chromatin remodeling, folding, and positioning in the nucleus" @default.
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- W4285384251 doi "https://doi.org/10.1016/j.pbi.2022.102261" @default.
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