FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285387588> ?p ?o ?g. }

• W4285387588 abstract "Background: Exercise is one of the most effective interventions for preventing and treating skeletal muscle aging. Exercise-induced autophagy is widely acknowledged to regulate skeletal muscle mass and delay skeletal muscle aging. However, the mechanisms underlying of the effect of different exercises on autophagy in aging skeletal muscle remain unclear. Methods: A systematic review was performed following an electronic search of SCOPUS, PubMed, Web of Science, ScienceDirect, and Google Scholar and two Chinese electronic databases, CNKI and Wan Fang. All articles published in English and Chinese between January 2010 and January 2022 that quantified autophagy-related proteins in aging skeletal muscle models. Results: The primary outcome was autophagy assessment, indicated by changes in the levels of any autophagy-associated proteins. A total of fifteen studies were included in the final review. Chronic exercise modes mainly comprise aerobic exercise and resistance exercise, and the intervention types include treadmill training, voluntary wheel running, and ladder training. LC3, Atg5-Atg7/9/12, mTOR, Beclin1, Bcl-2, p62, PGC-1α, and other protein levels were quantified, and the results showed that long-term aerobic exercise and resistance exercise could increase the expression of autophagy-related proteins in aging skeletal muscle (p < 0.05). However, there was no significant difference in short term or high-intensity chronic exercise, and different types and intensities of exercise yielded different levels of significance for autophagy-related protein expression. Conclusion: Existing evidence reveals that high-intensity exercise may induce excessive autophagy, while low-intensity exercise for a short period (Intervention duration <12 weeks, frequency <3 times/week) may not reach the threshold for exercise-induced autophagy. Precise control of the exercise dose is essential in the long term to maximize the benefits of exercise. Further investigation is warranted to explore the relationship between chronic exercise and different exercise duration and types to substantiate the delaying of skeletal muscle aging by exercise." @default.
• W4285387588 created "2022-07-14" @default.
• W4285387588 creator A5020782129 @default.
• W4285387588 creator A5023198563 @default.
• W4285387588 creator A5032170946 @default.
• W4285387588 creator A5043951752 @default.
• W4285387588 creator A5053933785 @default.
• W4285387588 creator A5080298585 @default.
• W4285387588 creator A5081897709 @default.
• W4285387588 date "2022-07-14" @default.
• W4285387588 modified "2023-10-05" @default.
• W4285387588 title "A Preclinical Systematic Review of the Effects of Chronic Exercise on Autophagy-Related Proteins in Aging Skeletal Muscle" @default.
• W4285387588 cites W1498724345 @default.
• W4285387588 cites W1813408973 @default.
• W4285387588 cites W1966382091 @default.
• W4285387588 cites W1983033348 @default.
• W4285387588 cites W1985127050 @default.
• W4285387588 cites W1999211990 @default.
• W4285387588 cites W2001045944 @default.
• W4285387588 cites W2012831734 @default.
• W4285387588 cites W2025109763 @default.
• W4285387588 cites W2040198130 @default.
• W4285387588 cites W2048771411 @default.
• W4285387588 cites W2049909030 @default.
• W4285387588 cites W2057731584 @default.
• W4285387588 cites W2060792177 @default.
• W4285387588 cites W2068554185 @default.
• W4285387588 cites W2102902846 @default.
• W4285387588 cites W2105126803 @default.
• W4285387588 cites W2134138119 @default.
• W4285387588 cites W2134386671 @default.
• W4285387588 cites W2137737168 @default.
• W4285387588 cites W2148836821 @default.
• W4285387588 cites W2150059080 @default.
• W4285387588 cites W2164577178 @default.
• W4285387588 cites W2165869751 @default.
• W4285387588 cites W2168551727 @default.
• W4285387588 cites W2171103810 @default.
• W4285387588 cites W2552756863 @default.
• W4285387588 cites W2562444161 @default.
• W4285387588 cites W2562684051 @default.
• W4285387588 cites W2588459414 @default.
• W4285387588 cites W2607049035 @default.
• W4285387588 cites W2743276212 @default.
• W4285387588 cites W2749634331 @default.
• W4285387588 cites W2779507721 @default.
• W4285387588 cites W2781977913 @default.
• W4285387588 cites W2794900649 @default.
• W4285387588 cites W2884054234 @default.
• W4285387588 cites W2902087935 @default.
• W4285387588 cites W2981213991 @default.
• W4285387588 cites W3095443272 @default.
• W4285387588 cites W3138973745 @default.
• W4285387588 cites W3162646626 @default.
• W4285387588 doi "https://doi.org/10.3389/fphys.2022.930185" @default.
• W4285387588 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35910582" @default.
• W4285387588 hasPublicationYear "2022" @default.
• W4285387588 type Work @default.
• W4285387588 citedByCount "2" @default.
• W4285387588 countsByYear W42853875882023 @default.
• W4285387588 crossrefType "journal-article" @default.
• W4285387588 hasAuthorship W4285387588A5020782129 @default.
• W4285387588 hasAuthorship W4285387588A5023198563 @default.
• W4285387588 hasAuthorship W4285387588A5032170946 @default.
• W4285387588 hasAuthorship W4285387588A5043951752 @default.
• W4285387588 hasAuthorship W4285387588A5053933785 @default.
• W4285387588 hasAuthorship W4285387588A5080298585 @default.
• W4285387588 hasAuthorship W4285387588A5081897709 @default.
• W4285387588 hasBestOaLocation W42853875881 @default.
• W4285387588 hasConcept C103038586 @default.
• W4285387588 hasConcept C126322002 @default.
• W4285387588 hasConcept C134018914 @default.
• W4285387588 hasConcept C190283241 @default.
• W4285387588 hasConcept C203522944 @default.
• W4285387588 hasConcept C2776811442 @default.
• W4285387588 hasConcept C2777953023 @default.
• W4285387588 hasConcept C2779959927 @default.
• W4285387588 hasConcept C2781000418 @default.
• W4285387588 hasConcept C55493867 @default.
• W4285387588 hasConcept C60644358 @default.
• W4285387588 hasConcept C71924100 @default.
• W4285387588 hasConcept C84393581 @default.
• W4285387588 hasConcept C86803240 @default.
• W4285387588 hasConceptScore W4285387588C103038586 @default.
• W4285387588 hasConceptScore W4285387588C126322002 @default.
• W4285387588 hasConceptScore W4285387588C134018914 @default.
• W4285387588 hasConceptScore W4285387588C190283241 @default.
• W4285387588 hasConceptScore W4285387588C203522944 @default.
• W4285387588 hasConceptScore W4285387588C2776811442 @default.
• W4285387588 hasConceptScore W4285387588C2777953023 @default.
• W4285387588 hasConceptScore W4285387588C2779959927 @default.
• W4285387588 hasConceptScore W4285387588C2781000418 @default.
• W4285387588 hasConceptScore W4285387588C55493867 @default.
• W4285387588 hasConceptScore W4285387588C60644358 @default.
• W4285387588 hasConceptScore W4285387588C71924100 @default.
• W4285387588 hasConceptScore W4285387588C84393581 @default.
• W4285387588 hasConceptScore W4285387588C86803240 @default.
• W4285387588 hasLocation W42853875881 @default.
• W4285387588 hasLocation W42853875882 @default.
• W4285387588 hasLocation W42853875883 @default.

• next