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• W4285388518 abstract "Duck plague virus (DPV), belonging to herpesviruses, is a linear double-stranded DNA virus. There are many reports about the outbreak of the duck plague in a variety of countries, which caused huge economic losses. Recently, increasing reports revealed that multiple long non-coding RNAs (lncRNAs) can possess great potential in the regulation of host antiviral immune response. Furthermore, it remains to be determined which specific molecular mechanisms are responsible for the DPV-host interaction in host immunity. Here, lncRNAs and mRNAs in DPV infected duck embryonic fibroblast (DEF) cells were identified by high-throughput RNA-sequencing (RNA-seq). And we predicted target genes of differentially expressed genes (DEGs) and formed a complex regulatory network depending on in-silico analysis and prediction.RNA-seq analysis results showed that 2921 lncRNAs were found at 30 h post-infection (hpi). In our study, 218 DE lncRNAs and 2840 DE mRNAs were obtained in DEF after DPV infection. Among these DEGs and target genes, some have been authenticated as immune-related molecules, such as a Macrophage mannose receptor (MR), Anas platyrhynchos toll-like receptor 2 (TLR2), leukocyte differentiation antigen, interleukin family, and their related regulatory factors. Furthermore, according to the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) enrichment analysis, we found that the target genes may have important effects on biological development, biosynthesis, signal transduction, cell biological regulation, and cell process. Also, we obtained, the potential targeting relationship existing in DEF cells between host lncRNAs and DPV-encoded miRNAs by software.This study revealed not only expression changes, but also the possible biological regulatory relationship of lncRNAs and mRNAs in DPV infected DEF cells. Together, these data and analyses provide additional insight into the role of lncRNAs and mRNAs in the host's immune response to DPV infection." @default.
• W4285388518 created "2022-07-14" @default.
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• W4285388518 date "2022-07-14" @default.
• W4285388518 modified "2023-10-10" @default.
• W4285388518 title "Differential expression profile and in-silico functional analysis of long noncoding RNA and mRNA in duck embryo fibroblasts infected with duck plague virus" @default.
• W4285388518 cites W185262400 @default.
• W4285388518 cites W1942658470 @default.
• W4285388518 cites W1974116356 @default.
• W4285388518 cites W1985209069 @default.
• W4285388518 cites W1993051112 @default.
• W4285388518 cites W1998422171 @default.
• W4285388518 cites W2009472173 @default.
• W4285388518 cites W2013219140 @default.
• W4285388518 cites W2013626663 @default.
• W4285388518 cites W2039917919 @default.
• W4285388518 cites W2044363505 @default.
• W4285388518 cites W2049689869 @default.
• W4285388518 cites W2050337099 @default.
• W4285388518 cites W2057596520 @default.
• W4285388518 cites W2061427860 @default.
• W4285388518 cites W2061548680 @default.
• W4285388518 cites W2075694474 @default.
• W4285388518 cites W2103017472 @default.
• W4285388518 cites W2104005232 @default.
• W4285388518 cites W2106641523 @default.
• W4285388518 cites W2107277218 @default.
• W4285388518 cites W2114787375 @default.
• W4285388518 cites W2119034410 @default.
• W4285388518 cites W2120456037 @default.
• W4285388518 cites W2122320678 @default.
• W4285388518 cites W2123060905 @default.
• W4285388518 cites W2133579817 @default.
• W4285388518 cites W2134526812 @default.
• W4285388518 cites W2144463869 @default.
• W4285388518 cites W2151082310 @default.
• W4285388518 cites W2156414024 @default.
• W4285388518 cites W2159675211 @default.
• W4285388518 cites W2160333540 @default.
• W4285388518 cites W2166820820 @default.
• W4285388518 cites W2170752267 @default.
• W4285388518 cites W2179438025 @default.
• W4285388518 cites W2192080449 @default.
• W4285388518 cites W2299835434 @default.
• W4285388518 cites W2322308790 @default.
• W4285388518 cites W2327437010 @default.
• W4285388518 cites W2341291028 @default.
• W4285388518 cites W2398423374 @default.
• W4285388518 cites W2417948652 @default.
• W4285388518 cites W2418307109 @default.
• W4285388518 cites W2505384565 @default.
• W4285388518 cites W2549899421 @default.
• W4285388518 cites W2586036588 @default.
• W4285388518 cites W2589576581 @default.
• W4285388518 cites W2593435098 @default.
• W4285388518 cites W266824605 @default.
• W4285388518 cites W2751361662 @default.
• W4285388518 cites W2766398869 @default.
• W4285388518 cites W2768979119 @default.
• W4285388518 cites W2784570320 @default.
• W4285388518 cites W2800692547 @default.
• W4285388518 cites W2801964202 @default.
• W4285388518 cites W2900470392 @default.
• W4285388518 cites W2910477505 @default.
• W4285388518 cites W2942809049 @default.
• W4285388518 cites W2989179371 @default.
• W4285388518 cites W3022671507 @default.
• W4285388518 cites W3042494141 @default.
• W4285388518 cites W3047259961 @default.
• W4285388518 cites W3084144015 @default.
• W4285388518 cites W3093708802 @default.
• W4285388518 cites W3095112007 @default.
• W4285388518 cites W3112207312 @default.
• W4285388518 cites W3162288631 @default.
• W4285388518 cites W3170143789 @default.
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• W4285388518 doi "https://doi.org/10.1186/s12864-022-08739-7" @default.
• W4285388518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35836133" @default.
• W4285388518 hasPublicationYear "2022" @default.
• W4285388518 type Work @default.

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