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• W4285392243 abstract "Our understanding of the immune responses that follow SARS-CoV-2 infection and vaccination has progressed considerably since the COVID-19 pandemic was first declared on the 11 th of March in 2020. Recovery from infection is associated with the development of protective immune responses, although over time these become less effective against new emerging SARS-CoV-2 variants. Consequently, reinfection with SARS-CoV-2 variants is not infrequent and has contributed to the ongoing pandemic. COVID-19 vaccines have had a tremendous impact on reducing infection and particularly the number of deaths associated with SARS-CoV-2 infection. However, waning of vaccine induced immunity plus the emergence of new variants has necessitated the use of boosters to maintain the benefits of vaccination in reducing COVID-19 associated deaths. Boosting is also beneficial for individuals who have recovered from COVID-19 and developed natural immunity, also enhancing responses immune responses to SARS-CoV-2 variants. This review summarizes our understanding of the immune responses that follow SARS-CoV-2 infection and vaccination, the risks of reinfection with emerging variants and the very important protective role vaccine boosting plays in both vaccinated and previously infected individuals." @default.
• W4285392243 created "2022-07-14" @default.
• W4285392243 creator A5027740877 @default.
• W4285392243 creator A5038228333 @default.
• W4285392243 creator A5047144498 @default.
• W4285392243 creator A5059806737 @default.
• W4285392243 date "2022-07-13" @default.
• W4285392243 modified "2023-09-26" @default.
• W4285392243 title "A Complementary Union of SARS-CoV2 Natural and Vaccine Induced Immune Responses" @default.
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