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- W4285403911 abstract "A new series of isoxazole fused thiazole-oxazole compounds (10a-j) have been designed synthesized and confirmed by 1HNMR, 13CNMR and mass spectral data. Further, all these derivatives were assessed for their in vitro anticancer properties against four human cancer cell lines including PC3 and DU-145 (prostate cancer), A549 (lung cancer) and breast cancer (MCF-7) by utilizing of MTT method. These results were compared with known chemotherapeutic agent etoposide. Most of the tested compounds displayed good to moderate anticancer activity as positive control. Particularly, four compounds 10a, 10b, 10c and 10 h showed prominent activity against." @default.
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- W4285403911 date "2022-10-01" @default.
- W4285403911 modified "2023-10-16" @default.
- W4285403911 title "Design, synthesis and anticancer evaluation of isoxazole fused thiazole-oxazole derivatives" @default.
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- W4285403911 doi "https://doi.org/10.1016/j.cdc.2022.100907" @default.
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