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- W4285405294 endingPage "150" @default.
- W4285405294 startingPage "141" @default.
- W4285405294 abstract "Reproductive aging is a natural process conserved across species and is well-known in females. It shows age-related follicle depletion and reduction of oocyte quality, eventually causing reproductive senescence and menopause. Although reproductive aging in males is not well noticed as in females, it also causes infertility and has deleterious consequences on the offspring. Various factors have been suggested to contribute to reproductive aging, including oxidative stress, mitochondrial defects, telomere shortening, meiotic chromosome segregation errors and genetic alterations. With the increasing trend of pregnancy age, it is particularly crucial to find interventions to preserve or extend human fertility. Studies in humans and model organisms have provided insights into the biological pathways associated with reproductive aging, and a series of potential interventive strategies have been tested. Here, we review factors affecting reproductive aging in females and males and summarize interventive strategies that may help delay or rescue the aging phenotypes of reproduction." @default.
- W4285405294 created "2022-07-14" @default.
- W4285405294 creator A5054464310 @default.
- W4285405294 creator A5087064575 @default.
- W4285405294 date "2023-03-01" @default.
- W4285405294 modified "2023-10-16" @default.
- W4285405294 title "Reproductive aging: biological pathways and potential interventive strategies" @default.
- W4285405294 cites W1845926721 @default.
- W4285405294 cites W1849835339 @default.
- W4285405294 cites W1904407543 @default.
- W4285405294 cites W1949822692 @default.
- W4285405294 cites W1959721425 @default.
- W4285405294 cites W1970334813 @default.
- W4285405294 cites W1971053085 @default.
- W4285405294 cites W1976153964 @default.
- W4285405294 cites W1984074400 @default.
- W4285405294 cites W1989877184 @default.
- W4285405294 cites W2009048098 @default.
- W4285405294 cites W2020331089 @default.
- W4285405294 cites W2033502012 @default.
- W4285405294 cites W2034205856 @default.
- W4285405294 cites W2040174223 @default.
- W4285405294 cites W2041944904 @default.
- W4285405294 cites W2044897807 @default.
- W4285405294 cites W2048776985 @default.
- W4285405294 cites W2077183638 @default.
- W4285405294 cites W2086446589 @default.
- W4285405294 cites W2087269413 @default.
- W4285405294 cites W2088491872 @default.
- W4285405294 cites W2092739399 @default.
- W4285405294 cites W2099544293 @default.
- W4285405294 cites W2120237080 @default.
- W4285405294 cites W2123037610 @default.
- W4285405294 cites W2130113892 @default.
- W4285405294 cites W2137160128 @default.
- W4285405294 cites W2140372014 @default.
- W4285405294 cites W2140906896 @default.
- W4285405294 cites W2141297150 @default.
- W4285405294 cites W2144687593 @default.
- W4285405294 cites W2147545348 @default.
- W4285405294 cites W2152588928 @default.
- W4285405294 cites W2155866830 @default.
- W4285405294 cites W2156001594 @default.
- W4285405294 cites W2157077875 @default.
- W4285405294 cites W2157784579 @default.
- W4285405294 cites W2158389310 @default.
- W4285405294 cites W2160402200 @default.
- W4285405294 cites W2161824187 @default.
- W4285405294 cites W2166535830 @default.
- W4285405294 cites W2167340008 @default.
- W4285405294 cites W2167450908 @default.
- W4285405294 cites W2169645813 @default.
- W4285405294 cites W2170051958 @default.
- W4285405294 cites W2274224330 @default.
- W4285405294 cites W2531660425 @default.
- W4285405294 cites W2534262503 @default.
- W4285405294 cites W2537290537 @default.
- W4285405294 cites W2593515715 @default.
- W4285405294 cites W2612104114 @default.
- W4285405294 cites W2733452409 @default.
- W4285405294 cites W2736487677 @default.
- W4285405294 cites W2774620560 @default.
- W4285405294 cites W2792808751 @default.
- W4285405294 cites W2803581370 @default.
- W4285405294 cites W2886452253 @default.
- W4285405294 cites W2906188826 @default.
- W4285405294 cites W2907381384 @default.
- W4285405294 cites W2908441418 @default.
- W4285405294 cites W2918825869 @default.
- W4285405294 cites W2965802963 @default.
- W4285405294 cites W2975979611 @default.
- W4285405294 cites W2989580053 @default.
- W4285405294 cites W2991083419 @default.
- W4285405294 cites W2991416247 @default.
- W4285405294 cites W3005675840 @default.
- W4285405294 cites W3007353835 @default.
- W4285405294 cites W3013029453 @default.
- W4285405294 cites W3017585151 @default.
- W4285405294 cites W3020166545 @default.
- W4285405294 cites W3028816559 @default.
- W4285405294 cites W3047258918 @default.
- W4285405294 cites W3112783119 @default.
- W4285405294 cites W3118285774 @default.
- W4285405294 cites W3125705540 @default.
- W4285405294 cites W3130482733 @default.
- W4285405294 cites W3134248247 @default.
- W4285405294 cites W3138764120 @default.
- W4285405294 cites W3185710912 @default.
- W4285405294 cites W3186442659 @default.
- W4285405294 cites W3197819978 @default.
- W4285405294 cites W3205997100 @default.
- W4285405294 cites W3206919694 @default.
- W4285405294 cites W3207098184 @default.
- W4285405294 cites W3207530155 @default.
- W4285405294 cites W3210011355 @default.
- W4285405294 cites W3212112646 @default.
- W4285405294 cites W4200195564 @default.
- W4285405294 cites W4200614630 @default.