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- W4285491501 abstract "Abstract Objective : Assessment of neurobehaviour and visual function of newborns with congenital heart disease during post-operative period to identify infants at risk of neurodevelopmental and visual impairment. Study design: Prospective study that include 45 newborns that underwent cardiac surgery. Newborn Behavioral Observations test (NBO) and “ML Battery of Optotypes” were used for assessment. Results : The median NBO global score was 2.4 [2.1-2.6]. Total days of oral morphine [p=0.005] and total days of sedation [p=0.009] were strongly related to abnormal evaluations. Time of cerebral regional oxygen saturation (CrSO2) under 40% during surgery and increased lactate were related with abnormal motor evaluation. Only 14.5% of the patients presented pathological results in visual evaluation. Conclusions : We have demonstrated alterations in attention, autonomic, motor and oral motor function. Duration of sedative medication, time of CrSO2 under 40% during surgery and increased lactate are the most important risk factors. No significant visual impairment was detected." @default.
- W4285491501 created "2022-07-15" @default.
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- W4285491501 date "2022-07-15" @default.
- W4285491501 modified "2023-10-16" @default.
- W4285491501 title "Early post-operative neurodevelopment and visual assessment in neonates with congenital heart disease undergoing cardiac surgery" @default.
- W4285491501 doi "https://doi.org/10.21203/rs.3.rs-1827282/v1" @default.
- W4285491501 hasPublicationYear "2022" @default.
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