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- W4285492080 abstract "Herein, we demonstrated the oxidative cross-dehydrogenative coupling between amidines and chalcones catalyzed by flavin and iodine. The riboflavin-iodine catalytic system played multiple roles in substrate- and O2-activation, enabling the facile and atom-economical synthesis of tetra-substituted imidazoles in good yields (60-87%). This metal-free reaction consumed only 1 equiv of molecular oxygen and generated 2 equiv of environmentally benign H2O as the only byproduct." @default.
- W4285492080 created "2022-07-15" @default.
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- W4285492080 date "2022-07-15" @default.
- W4285492080 modified "2023-09-27" @default.
- W4285492080 title "Metal-Free Atom-Economical Synthesis of Tetra-Substituted Imidazoles via Flavin-Iodine Catalyzed Aerobic Cross-Dehydrogenative Coupling of Amidines and Chalcones" @default.
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- W4285492080 doi "https://doi.org/10.1021/acs.joc.2c00596" @default.
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