Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285492762> ?p ?o ?g. }
- W4285492762 endingPage "9243" @default.
- W4285492762 startingPage "9238" @default.
- W4285492762 abstract "The hydrogenation of carboxylic acids to alcohols is of great significance in synthetic chemistry. Reported herein are competent iridium catalysts [Cp*Ir(N,N′)(H2O)][OTf]2 (N,N′ = three different 2,2′-bi-1,4,5,6-tetrahydropyrimidines) for application in the catalytic hydrogenation of a series of alkyl carboxylic acids under mild conditions (25–100 °C) without any additives. Among these structurally diverse catalysts evaluated for reactivity, complex 4 bearing an electron-deficient ligand (N,N′ = 2,2′-bi-5,5′-hydroxyl-1,4,5,6-tetrahydropyrimidine) is the most robust, which can hydrogenate acetic acid smoothly at 25 °C to give the alcohol and ester products with a TON of 1106. Detailed mechanistic studies suggest that the generation of an [Ir–H] intermediate is involved in the rate-limiting step. With this catalyst system, a broad range of alkyl carboxylic acids were hydrogenated with moderate to high TONs." @default.
- W4285492762 created "2022-07-15" @default.
- W4285492762 creator A5011065863 @default.
- W4285492762 creator A5053746291 @default.
- W4285492762 creator A5069522797 @default.
- W4285492762 creator A5074745455 @default.
- W4285492762 date "2022-07-15" @default.
- W4285492762 modified "2023-10-11" @default.
- W4285492762 title "Hydrogenation of Alkyl Carboxylic Acids with Tetrahydropyrimidine-Derived Iridium Complexes under Mild Conditions" @default.
- W4285492762 cites W1910262408 @default.
- W4285492762 cites W1970824135 @default.
- W4285492762 cites W1977041441 @default.
- W4285492762 cites W1985375294 @default.
- W4285492762 cites W1990217026 @default.
- W4285492762 cites W2040397319 @default.
- W4285492762 cites W2049627362 @default.
- W4285492762 cites W2061382464 @default.
- W4285492762 cites W2085639342 @default.
- W4285492762 cites W2109977502 @default.
- W4285492762 cites W2114774477 @default.
- W4285492762 cites W2129758402 @default.
- W4285492762 cites W2146240505 @default.
- W4285492762 cites W2149570038 @default.
- W4285492762 cites W2166925424 @default.
- W4285492762 cites W2172107557 @default.
- W4285492762 cites W2231294870 @default.
- W4285492762 cites W2262145552 @default.
- W4285492762 cites W2270992526 @default.
- W4285492762 cites W2323163306 @default.
- W4285492762 cites W2326822579 @default.
- W4285492762 cites W2397179710 @default.
- W4285492762 cites W2482217236 @default.
- W4285492762 cites W2621528101 @default.
- W4285492762 cites W2790374921 @default.
- W4285492762 cites W2894988706 @default.
- W4285492762 cites W2987762707 @default.
- W4285492762 cites W3093878017 @default.
- W4285492762 cites W3136832502 @default.
- W4285492762 cites W4207014942 @default.
- W4285492762 doi "https://doi.org/10.1021/acscatal.2c01606" @default.
- W4285492762 hasPublicationYear "2022" @default.
- W4285492762 type Work @default.
- W4285492762 citedByCount "0" @default.
- W4285492762 crossrefType "journal-article" @default.
- W4285492762 hasAuthorship W4285492762A5011065863 @default.
- W4285492762 hasAuthorship W4285492762A5053746291 @default.
- W4285492762 hasAuthorship W4285492762A5069522797 @default.
- W4285492762 hasAuthorship W4285492762A5074745455 @default.
- W4285492762 hasConcept C116569031 @default.
- W4285492762 hasConcept C142724271 @default.
- W4285492762 hasConcept C155647269 @default.
- W4285492762 hasConcept C161790260 @default.
- W4285492762 hasConcept C170493617 @default.
- W4285492762 hasConcept C178790620 @default.
- W4285492762 hasConcept C185592680 @default.
- W4285492762 hasConcept C204787440 @default.
- W4285492762 hasConcept C2776673659 @default.
- W4285492762 hasConcept C2776910235 @default.
- W4285492762 hasConcept C2779074116 @default.
- W4285492762 hasConcept C2780263894 @default.
- W4285492762 hasConcept C2781066024 @default.
- W4285492762 hasConcept C528581852 @default.
- W4285492762 hasConcept C55493867 @default.
- W4285492762 hasConcept C71924100 @default.
- W4285492762 hasConceptScore W4285492762C116569031 @default.
- W4285492762 hasConceptScore W4285492762C142724271 @default.
- W4285492762 hasConceptScore W4285492762C155647269 @default.
- W4285492762 hasConceptScore W4285492762C161790260 @default.
- W4285492762 hasConceptScore W4285492762C170493617 @default.
- W4285492762 hasConceptScore W4285492762C178790620 @default.
- W4285492762 hasConceptScore W4285492762C185592680 @default.
- W4285492762 hasConceptScore W4285492762C204787440 @default.
- W4285492762 hasConceptScore W4285492762C2776673659 @default.
- W4285492762 hasConceptScore W4285492762C2776910235 @default.
- W4285492762 hasConceptScore W4285492762C2779074116 @default.
- W4285492762 hasConceptScore W4285492762C2780263894 @default.
- W4285492762 hasConceptScore W4285492762C2781066024 @default.
- W4285492762 hasConceptScore W4285492762C528581852 @default.
- W4285492762 hasConceptScore W4285492762C55493867 @default.
- W4285492762 hasConceptScore W4285492762C71924100 @default.
- W4285492762 hasFunder F4320321001 @default.
- W4285492762 hasIssue "15" @default.
- W4285492762 hasLocation W42854927621 @default.
- W4285492762 hasOpenAccess W4285492762 @default.
- W4285492762 hasPrimaryLocation W42854927621 @default.
- W4285492762 hasRelatedWork W1929248663 @default.
- W4285492762 hasRelatedWork W1969039155 @default.
- W4285492762 hasRelatedWork W2069683629 @default.
- W4285492762 hasRelatedWork W2339331248 @default.
- W4285492762 hasRelatedWork W2347787025 @default.
- W4285492762 hasRelatedWork W2375132534 @default.
- W4285492762 hasRelatedWork W2387970328 @default.
- W4285492762 hasRelatedWork W2918806445 @default.
- W4285492762 hasRelatedWork W2920131620 @default.
- W4285492762 hasRelatedWork W2977911848 @default.
- W4285492762 hasVolume "12" @default.
- W4285492762 isParatext "false" @default.
- W4285492762 isRetracted "false" @default.