FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285493896> ?p ?o ?g. }

• W4285493896 abstract "Objectives The relationship between preoperative serum uric acid (SUA) and cerebrospinal fluid (CSF) Alzheimer-related biomarkers were investigated to determine whether high SUA is a potential risk factor for postoperative delirium (POD) and to evaluate its predictive efficacy. Methods The participants were selected from the Perioperative Neurocognitive Disorder Risk Factor and Prognosis (PNDRFAP) study and the Perioperative Neurocognitive Disorder and Biomarker Lifestyle (PNDABLE) study. The logistic regression equation was used to analyze the risk factors and protective factors of POD. The interaction term (SUA × Sex) was introduced into the linear model to explore the potential modification effects of sex on the identified correlations. We analyzed the mediating effects of Alzheimer-related biomarkers. Finally, we constructed the receiver operating characteristic (ROC) curve and the nomogram model to evaluate the efficacy of SUA and Alzheimer-related biomarkers in predicting POD. Results Patients with POD had elevated SUA level (PNDRFAP: p = 0.002, PNDABLE: p &lt; 0.001). Preoperative SUA level was positively correlated with CSF phosphorylated tau (P-tau) ( p = 0.027) and β-amyloid42 (Aβ 42 )/P-tau ( p = 0.023). Interaction analysis did not find any modification effect of sex. The relationship between SUA and POD was partially mediated by CSF P-tau (15.3%). ROC curve showed that the model combining SUA and Alzheimer-related biomarkers had better performance in predicting POD [area under the curve (AUC) = 0.880; p &lt; 0.001], and the predictive model is accurate. Conclusions High SUA may enhance CSF P-tau level, thus increasing the risk of POD, and the model combining SUA and Alzheimer-related biomarkers can accurately predict the occurrence of POD." @default.
• W4285493896 created "2022-07-15" @default.
• W4285493896 creator A5001584819 @default.
• W4285493896 creator A5018251349 @default.
• W4285493896 creator A5018703835 @default.
• W4285493896 creator A5036458654 @default.
• W4285493896 creator A5040961908 @default.
• W4285493896 creator A5042748373 @default.
• W4285493896 creator A5069750573 @default.
• W4285493896 creator A5072452964 @default.
• W4285493896 creator A5086529957 @default.
• W4285493896 date "2022-07-14" @default.
• W4285493896 modified "2023-10-17" @default.
• W4285493896 title "Potential Value of Serum Uric Acid in the Identification of Postoperative Delirium in Geriatric Patients Undergoing Knee Replacement" @default.
• W4285493896 cites W1209385844 @default.
• W4285493896 cites W1600934558 @default.
• W4285493896 cites W1757828763 @default.
• W4285493896 cites W1963700573 @default.
• W4285493896 cites W1969939093 @default.
• W4285493896 cites W2011785069 @default.
• W4285493896 cites W2032440627 @default.
• W4285493896 cites W2059129919 @default.
• W4285493896 cites W2061024885 @default.
• W4285493896 cites W2069812964 @default.
• W4285493896 cites W2081033553 @default.
• W4285493896 cites W2103913904 @default.
• W4285493896 cites W2104276961 @default.
• W4285493896 cites W2118234970 @default.
• W4285493896 cites W2126402425 @default.
• W4285493896 cites W2132066584 @default.
• W4285493896 cites W2151769480 @default.
• W4285493896 cites W2152845974 @default.
• W4285493896 cites W2162540399 @default.
• W4285493896 cites W2185034389 @default.
• W4285493896 cites W2186679182 @default.
• W4285493896 cites W2216742501 @default.
• W4285493896 cites W2312421263 @default.
• W4285493896 cites W2323342936 @default.
• W4285493896 cites W2344340306 @default.
• W4285493896 cites W2526152871 @default.
• W4285493896 cites W2544376246 @default.
• W4285493896 cites W2748622848 @default.
• W4285493896 cites W2805858230 @default.
• W4285493896 cites W3021032572 @default.
• W4285493896 cites W3115742614 @default.
• W4285493896 cites W3127824905 @default.
• W4285493896 cites W3170172610 @default.
• W4285493896 cites W4205630763 @default.
• W4285493896 cites W4220921830 @default.
• W4285493896 cites W4256717476 @default.
• W4285493896 cites W52227880 @default.
• W4285493896 cites W3174461150 @default.
• W4285493896 doi "https://doi.org/10.3389/fnagi.2022.909738" @default.
• W4285493896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35912084" @default.
• W4285493896 hasPublicationYear "2022" @default.
• W4285493896 type Work @default.
• W4285493896 citedByCount "1" @default.
• W4285493896 countsByYear W42854938962023 @default.
• W4285493896 crossrefType "journal-article" @default.
• W4285493896 hasAuthorship W4285493896A5001584819 @default.
• W4285493896 hasAuthorship W4285493896A5018251349 @default.
• W4285493896 hasAuthorship W4285493896A5018703835 @default.
• W4285493896 hasAuthorship W4285493896A5036458654 @default.
• W4285493896 hasAuthorship W4285493896A5040961908 @default.
• W4285493896 hasAuthorship W4285493896A5042748373 @default.
• W4285493896 hasAuthorship W4285493896A5069750573 @default.
• W4285493896 hasAuthorship W4285493896A5072452964 @default.
• W4285493896 hasAuthorship W4285493896A5086529957 @default.
• W4285493896 hasBestOaLocation W42854938961 @default.
• W4285493896 hasConcept C118552586 @default.
• W4285493896 hasConcept C126322002 @default.
• W4285493896 hasConcept C137776501 @default.
• W4285493896 hasConcept C141071460 @default.
• W4285493896 hasConcept C143998085 @default.
• W4285493896 hasConcept C151956035 @default.
• W4285493896 hasConcept C169900460 @default.
• W4285493896 hasConcept C172467417 @default.
• W4285493896 hasConcept C185592680 @default.
• W4285493896 hasConcept C2779753318 @default.
• W4285493896 hasConcept C2779881121 @default.
• W4285493896 hasConcept C2781197716 @default.
• W4285493896 hasConcept C31174226 @default.
• W4285493896 hasConcept C50440223 @default.
• W4285493896 hasConcept C55493867 @default.
• W4285493896 hasConcept C58471807 @default.
• W4285493896 hasConcept C6557445 @default.
• W4285493896 hasConcept C71924100 @default.
• W4285493896 hasConcept C76318530 @default.
• W4285493896 hasConcept C86803240 @default.
• W4285493896 hasConcept C90924648 @default.
• W4285493896 hasConceptScore W4285493896C118552586 @default.
• W4285493896 hasConceptScore W4285493896C126322002 @default.
• W4285493896 hasConceptScore W4285493896C137776501 @default.
• W4285493896 hasConceptScore W4285493896C141071460 @default.
• W4285493896 hasConceptScore W4285493896C143998085 @default.
• W4285493896 hasConceptScore W4285493896C151956035 @default.
• W4285493896 hasConceptScore W4285493896C169900460 @default.
• W4285493896 hasConceptScore W4285493896C172467417 @default.
• W4285493896 hasConceptScore W4285493896C185592680 @default.
• W4285493896 hasConceptScore W4285493896C2779753318 @default.

• next