FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285495380> ?p ?o ?g. }

• W4285495380 endingPage "2144" @default.
• W4285495380 startingPage "2124" @default.
• W4285495380 abstract "Spinal cord injury (SCI) leads to severe loss of motor and sensory functions, and the rehabilitation of SCI is a worldwide problem. Tissue-engineered scaffolds offer new hope for SCI patients, while the newly developed materials encountered a challenge in modeling the microenvironment around the lesion site. We constructed a new composite scaffold by mixing decellularized spinal cord extracellular matrix (dECM) with gelatin methacryloyl (GelMA). The dECM, as a natural biological material, retained a large number of proteins and growth factors related to neurogenesis. GelMA was a photopolymerizable material, harbored a polymer network structure, soft texture, certain shape and plenty of water. The viability, proliferation, and differentiation of neural stem cells (NSCs) on the composite scaffold were evaluated by cell count kit-8 (CCK8), Live/Dead assay, phalloidin staining, 5-Ethynyl-2'-deoxyurdine (EdU), immunofluorescence staining and western blot. The Live/Dead assay, phalloidin staining, EdU, and CCK8 assay showed that the composite scaffold had good biocompatibility and provided better support for proliferation of NSCs. Results of immunocytochemistry and western blot showed that the composite scaffolds promoted the specific differentiation of NSCs into neuron cells. Together, this dECM/GelMA composite scaffold can be used as a cell culture coating, the isolated NSCs seeded on the surface of composite scaffold expressed neuronal markers and assumed neuronal morphology. Our work provided a new method that would be widely used in tissue engineering of SCI." @default.
• W4285495380 created "2022-07-15" @default.
• W4285495380 creator A5000290591 @default.
• W4285495380 creator A5003647086 @default.
• W4285495380 creator A5037902083 @default.
• W4285495380 creator A5040704279 @default.
• W4285495380 creator A5061526820 @default.
• W4285495380 creator A5071316360 @default.
• W4285495380 creator A5074183225 @default.
• W4285495380 creator A5083304059 @default.
• W4285495380 creator A5090366405 @default.
• W4285495380 creator A5091887347 @default.
• W4285495380 date "2022-07-23" @default.
• W4285495380 modified "2023-10-17" @default.
• W4285495380 title "Construction of a decellularized spinal cord matrix/GelMA composite scaffold and its effects on neuronal differentiation of neural stem cells" @default.
• W4285495380 cites W1566509581 @default.
• W4285495380 cites W1935012038 @default.
• W4285495380 cites W1966609926 @default.
• W4285495380 cites W1976491651 @default.
• W4285495380 cites W1978125793 @default.
• W4285495380 cites W2008435056 @default.
• W4285495380 cites W2020539766 @default.
• W4285495380 cites W2030804101 @default.
• W4285495380 cites W2058290557 @default.
• W4285495380 cites W2059486645 @default.
• W4285495380 cites W2067218748 @default.
• W4285495380 cites W2101865710 @default.
• W4285495380 cites W2126111746 @default.
• W4285495380 cites W2138782310 @default.
• W4285495380 cites W2146646647 @default.
• W4285495380 cites W2229689447 @default.
• W4285495380 cites W2314454902 @default.
• W4285495380 cites W2484283047 @default.
• W4285495380 cites W2556807216 @default.
• W4285495380 cites W2560656096 @default.
• W4285495380 cites W2739841472 @default.
• W4285495380 cites W2791058678 @default.
• W4285495380 cites W2793872215 @default.
• W4285495380 cites W2801198579 @default.
• W4285495380 cites W2802189972 @default.
• W4285495380 cites W2883519830 @default.
• W4285495380 cites W2889283495 @default.
• W4285495380 cites W2908359749 @default.
• W4285495380 cites W2944358961 @default.
• W4285495380 cites W2946906538 @default.
• W4285495380 cites W2950871813 @default.
• W4285495380 cites W2971180467 @default.
• W4285495380 cites W2982487149 @default.
• W4285495380 cites W3005097055 @default.
• W4285495380 cites W3006443690 @default.
• W4285495380 cites W3026894180 @default.
• W4285495380 cites W3034045077 @default.
• W4285495380 cites W3046934626 @default.
• W4285495380 cites W3047934165 @default.
• W4285495380 cites W3087372159 @default.
• W4285495380 cites W3087718534 @default.
• W4285495380 cites W3092302207 @default.
• W4285495380 cites W3104511537 @default.
• W4285495380 cites W3105722743 @default.
• W4285495380 cites W3110541118 @default.
• W4285495380 cites W3112146213 @default.
• W4285495380 cites W3112730169 @default.
• W4285495380 cites W3126960072 @default.
• W4285495380 cites W3146426336 @default.
• W4285495380 cites W3188402380 @default.
• W4285495380 cites W3197832247 @default.
• W4285495380 cites W3207169976 @default.
• W4285495380 cites W4206703625 @default.
• W4285495380 cites W865369452 @default.
• W4285495380 doi "https://doi.org/10.1080/09205063.2022.2102275" @default.
• W4285495380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35835455" @default.
• W4285495380 hasPublicationYear "2022" @default.
• W4285495380 type Work @default.
• W4285495380 citedByCount "1" @default.
• W4285495380 countsByYear W42854953802023 @default.
• W4285495380 crossrefType "journal-article" @default.
• W4285495380 hasAuthorship W4285495380A5000290591 @default.
• W4285495380 hasAuthorship W4285495380A5003647086 @default.
• W4285495380 hasAuthorship W4285495380A5037902083 @default.
• W4285495380 hasAuthorship W4285495380A5040704279 @default.
• W4285495380 hasAuthorship W4285495380A5061526820 @default.
• W4285495380 hasAuthorship W4285495380A5071316360 @default.
• W4285495380 hasAuthorship W4285495380A5074183225 @default.
• W4285495380 hasAuthorship W4285495380A5083304059 @default.
• W4285495380 hasAuthorship W4285495380A5090366405 @default.
• W4285495380 hasAuthorship W4285495380A5091887347 @default.
• W4285495380 hasConcept C136229726 @default.
• W4285495380 hasConcept C136834591 @default.
• W4285495380 hasConcept C169760540 @default.
• W4285495380 hasConcept C185592680 @default.
• W4285495380 hasConcept C187761678 @default.
• W4285495380 hasConcept C189165786 @default.
• W4285495380 hasConcept C190672674 @default.
• W4285495380 hasConcept C192562407 @default.
• W4285495380 hasConcept C2778334475 @default.
• W4285495380 hasConcept C2780775167 @default.
• W4285495380 hasConcept C28328180 @default.
• W4285495380 hasConcept C49892992 @default.

• next