Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285496810> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4285496810 endingPage "159" @default.
- W4285496810 startingPage "157" @default.
- W4285496810 abstract "Background: White matter hyperintensities (WMHs) are linked to cognitive decline and stroke. We investigate the impact of race on WMH progression in the Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes (ACCORDION MIND) trial. Materials and Methods: The primary outcome is WMH progression in milliliters, evaluated by fitting linear regression to WMH volume on the month 80 magnetic resonance imaging (MRI) and including the WMH volume on the baseline MRI. The primary predictor is patient race, with the exclusion of patients defined as “other” race. We also derived predicted probabilities of our outcome for systolic blood pressure (SBP) levels. Results: We included 276 patients who completed the baseline and month 80 MRI, of which 207 (75%) were White, 48 (17%) Black, and 21 (8%) Hispanic. During follow-up, the mean number of SBP, low-density lipoprotein (LDL), and A1c measurements per patient was 21, 8, and 15. The median (IQR) WMH progression was 1.5 mL (0.5 to 3.9) for Black patients, 1.0 mL (0.4 to 4.0) for Hispanics, and 1.3 mL (0.5 to 2.7) for Whites (Kruskal-Wallis test, P =0.59). In the multivariate regression model, Black, compared with White, patients had significantly more WMH progression (β Coefficient 1.26, 95% confidence interval 0.45 to 2.06, P =0.002). Hispanic, compared with White, patients neither have significantly different WMH progression ( P =0.392), nor was there a difference when comparing Hispanic to Black patients ( P =0.162). The predicted WMH progression was significantly higher for Black compared with White patients across a mean SBP of 117 to 139 mm Hg. Conclusions: Black diabetic patients in Action to Control Cardiovascular Risk in Diabetes Memory in Diabetes (ACCORDION MIND) have a higher risk of WMH progression than White patients across a normal range of SBP." @default.
- W4285496810 created "2022-07-15" @default.
- W4285496810 creator A5053098139 @default.
- W4285496810 creator A5054587412 @default.
- W4285496810 creator A5056529805 @default.
- W4285496810 creator A5058647871 @default.
- W4285496810 creator A5089350896 @default.
- W4285496810 date "2022-07-12" @default.
- W4285496810 modified "2023-10-14" @default.
- W4285496810 title "Racial/Ethnic Variation in White Matter Hyperintensity Progression in the ACCORDION MIND Study" @default.
- W4285496810 cites W1976312033 @default.
- W4285496810 cites W1985912112 @default.
- W4285496810 cites W2043115154 @default.
- W4285496810 cites W2047185449 @default.
- W4285496810 cites W2048507870 @default.
- W4285496810 cites W2162453950 @default.
- W4285496810 cites W2300209210 @default.
- W4285496810 cites W2338817723 @default.
- W4285496810 cites W2535727391 @default.
- W4285496810 cites W2898320157 @default.
- W4285496810 cites W2921782384 @default.
- W4285496810 cites W2954048457 @default.
- W4285496810 cites W2954315288 @default.
- W4285496810 cites W2975264918 @default.
- W4285496810 cites W3094435518 @default.
- W4285496810 cites W3194131243 @default.
- W4285496810 cites W4361980435 @default.
- W4285496810 doi "https://doi.org/10.1097/nrl.0000000000000454" @default.
- W4285496810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35834785" @default.
- W4285496810 hasPublicationYear "2022" @default.
- W4285496810 type Work @default.
- W4285496810 citedByCount "0" @default.
- W4285496810 crossrefType "journal-article" @default.
- W4285496810 hasAuthorship W4285496810A5053098139 @default.
- W4285496810 hasAuthorship W4285496810A5054587412 @default.
- W4285496810 hasAuthorship W4285496810A5056529805 @default.
- W4285496810 hasAuthorship W4285496810A5058647871 @default.
- W4285496810 hasAuthorship W4285496810A5089350896 @default.
- W4285496810 hasConcept C119857082 @default.
- W4285496810 hasConcept C126322002 @default.
- W4285496810 hasConcept C126838900 @default.
- W4285496810 hasConcept C134018914 @default.
- W4285496810 hasConcept C143409427 @default.
- W4285496810 hasConcept C146638467 @default.
- W4285496810 hasConcept C164705383 @default.
- W4285496810 hasConcept C2781192897 @default.
- W4285496810 hasConcept C41008148 @default.
- W4285496810 hasConcept C44249647 @default.
- W4285496810 hasConcept C48921125 @default.
- W4285496810 hasConcept C50382708 @default.
- W4285496810 hasConcept C555293320 @default.
- W4285496810 hasConcept C64946054 @default.
- W4285496810 hasConcept C71924100 @default.
- W4285496810 hasConceptScore W4285496810C119857082 @default.
- W4285496810 hasConceptScore W4285496810C126322002 @default.
- W4285496810 hasConceptScore W4285496810C126838900 @default.
- W4285496810 hasConceptScore W4285496810C134018914 @default.
- W4285496810 hasConceptScore W4285496810C143409427 @default.
- W4285496810 hasConceptScore W4285496810C146638467 @default.
- W4285496810 hasConceptScore W4285496810C164705383 @default.
- W4285496810 hasConceptScore W4285496810C2781192897 @default.
- W4285496810 hasConceptScore W4285496810C41008148 @default.
- W4285496810 hasConceptScore W4285496810C44249647 @default.
- W4285496810 hasConceptScore W4285496810C48921125 @default.
- W4285496810 hasConceptScore W4285496810C50382708 @default.
- W4285496810 hasConceptScore W4285496810C555293320 @default.
- W4285496810 hasConceptScore W4285496810C64946054 @default.
- W4285496810 hasConceptScore W4285496810C71924100 @default.
- W4285496810 hasIssue "3" @default.
- W4285496810 hasLocation W42854968101 @default.
- W4285496810 hasLocation W42854968102 @default.
- W4285496810 hasOpenAccess W4285496810 @default.
- W4285496810 hasPrimaryLocation W42854968101 @default.
- W4285496810 hasRelatedWork W1972935936 @default.
- W4285496810 hasRelatedWork W1993468227 @default.
- W4285496810 hasRelatedWork W2030227264 @default.
- W4285496810 hasRelatedWork W2040809088 @default.
- W4285496810 hasRelatedWork W2045661260 @default.
- W4285496810 hasRelatedWork W2497977495 @default.
- W4285496810 hasRelatedWork W2772033121 @default.
- W4285496810 hasRelatedWork W2791785058 @default.
- W4285496810 hasRelatedWork W2901959336 @default.
- W4285496810 hasRelatedWork W8770351 @default.
- W4285496810 hasVolume "28" @default.
- W4285496810 isParatext "false" @default.
- W4285496810 isRetracted "false" @default.
- W4285496810 workType "article" @default.