Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285499079> ?p ?o ?g. }
- W4285499079 endingPage "127127" @default.
- W4285499079 startingPage "127127" @default.
- W4285499079 abstract "Antibiotics, the primary drugs used to cure bacterial diseases, are increasingly becoming ineffective due to the emergence of multiple drug resistance (MDR) leading to recurrence of previously sensitive pathogens. Human gut microbiome (GM), known to play an important role in various physiological processes, consists of pool of diverse microbes. Indiscriminate use of antibiotics during the life span of an individual may lead to development of resistant microbes e.g. Vibrio, Acinetobacter, Escherichia, Klebsiella, Clostridia, etc. in the human GM. Transmission of antibiotic resistant genes (ARGs) between pathogenic and commensal bacteria occurs more frequently in microbiome communities wherein bacteria communicate and exchange cellular constituents both among themselves and with the host. Additionally, co-factors like 'early vs. late' exposure, type of antibiotics and duration of treatment modulate the adverse effects of antibiotics on GM maturation. Furthermore, factors like mode of birth, ethnicity, malnutrition, demography, diet, lifestyle, etc., which influence GM composition, can also indirectly alter the host response to antibiotics. Currently, advanced 'omics' and culturomics approaches are revealing novel avenues to study the interplay between antibiotics and the microbiome and to identify resistant genes in these bacterial communities. Here, we discuss the recent developments that have given insights into the effects of antibiotics on the homeostatic balance of the gut microbiome and thus on human health." @default.
- W4285499079 created "2022-07-15" @default.
- W4285499079 creator A5013423331 @default.
- W4285499079 creator A5031417794 @default.
- W4285499079 creator A5033517487 @default.
- W4285499079 creator A5048664788 @default.
- W4285499079 creator A5051343863 @default.
- W4285499079 creator A5074599207 @default.
- W4285499079 creator A5090447123 @default.
- W4285499079 date "2022-10-01" @default.
- W4285499079 modified "2023-10-09" @default.
- W4285499079 title "Emerging frontiers of antibiotics use and their impacts on the human gut microbiome" @default.
- W4285499079 cites W1577826155 @default.
- W4285499079 cites W1963849807 @default.
- W4285499079 cites W1967821667 @default.
- W4285499079 cites W1977591727 @default.
- W4285499079 cites W2003636767 @default.
- W4285499079 cites W2023506796 @default.
- W4285499079 cites W2028789388 @default.
- W4285499079 cites W2032605132 @default.
- W4285499079 cites W2090728933 @default.
- W4285499079 cites W2091588484 @default.
- W4285499079 cites W2109744701 @default.
- W4285499079 cites W2110189329 @default.
- W4285499079 cites W2111990189 @default.
- W4285499079 cites W2113131541 @default.
- W4285499079 cites W2113787438 @default.
- W4285499079 cites W2115545574 @default.
- W4285499079 cites W2125826054 @default.
- W4285499079 cites W2128769815 @default.
- W4285499079 cites W2128799206 @default.
- W4285499079 cites W2131781913 @default.
- W4285499079 cites W2133211145 @default.
- W4285499079 cites W2134985690 @default.
- W4285499079 cites W2137090067 @default.
- W4285499079 cites W2138497901 @default.
- W4285499079 cites W2140993771 @default.
- W4285499079 cites W2145669701 @default.
- W4285499079 cites W2155860422 @default.
- W4285499079 cites W2156522926 @default.
- W4285499079 cites W2163381573 @default.
- W4285499079 cites W2165043209 @default.
- W4285499079 cites W2279413689 @default.
- W4285499079 cites W2345430760 @default.
- W4285499079 cites W2359747920 @default.
- W4285499079 cites W2403573949 @default.
- W4285499079 cites W2428833938 @default.
- W4285499079 cites W2500271699 @default.
- W4285499079 cites W2529282553 @default.
- W4285499079 cites W2555648610 @default.
- W4285499079 cites W2606692795 @default.
- W4285499079 cites W2728376104 @default.
- W4285499079 cites W2739852532 @default.
- W4285499079 cites W2746392566 @default.
- W4285499079 cites W2753247826 @default.
- W4285499079 cites W2780732116 @default.
- W4285499079 cites W2787902098 @default.
- W4285499079 cites W2792771031 @default.
- W4285499079 cites W2807270740 @default.
- W4285499079 cites W2883224035 @default.
- W4285499079 cites W2884737885 @default.
- W4285499079 cites W2884844397 @default.
- W4285499079 cites W2884875610 @default.
- W4285499079 cites W2886557383 @default.
- W4285499079 cites W2887948975 @default.
- W4285499079 cites W2888423719 @default.
- W4285499079 cites W2889977344 @default.
- W4285499079 cites W2890046827 @default.
- W4285499079 cites W2891057921 @default.
- W4285499079 cites W2891585489 @default.
- W4285499079 cites W2894062910 @default.
- W4285499079 cites W2900586393 @default.
- W4285499079 cites W2901632635 @default.
- W4285499079 cites W2903406988 @default.
- W4285499079 cites W2912940347 @default.
- W4285499079 cites W2925165927 @default.
- W4285499079 cites W2929404193 @default.
- W4285499079 cites W2939868250 @default.
- W4285499079 cites W2940744886 @default.
- W4285499079 cites W2944348781 @default.
- W4285499079 cites W2949947154 @default.
- W4285499079 cites W2951189048 @default.
- W4285499079 cites W2952557828 @default.
- W4285499079 cites W2969339974 @default.
- W4285499079 cites W2973077148 @default.
- W4285499079 cites W2980721239 @default.
- W4285499079 cites W2981117779 @default.
- W4285499079 cites W2985983397 @default.
- W4285499079 cites W2993476941 @default.
- W4285499079 cites W2997602158 @default.
- W4285499079 cites W3000290005 @default.
- W4285499079 cites W3001171623 @default.
- W4285499079 cites W3001781379 @default.
- W4285499079 cites W3003477302 @default.
- W4285499079 cites W3003532967 @default.
- W4285499079 cites W3005762667 @default.
- W4285499079 cites W3005872316 @default.
- W4285499079 cites W3015992957 @default.