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- W4285586711 abstract "The opioid addiction epidemic has been an ongoing problem in the United States, with rates of opioid-related deaths continuing to rise across most of the country.1 Physician prescribing of narcotic pain medications, specifically following surgical procedures, has been shown to play a role in development of opioid addiction and abuse.2 Pain control following surgical procedures is important, but multiple studies in the plastic surgery literature have shown that overprescribing of opioids is an issue in which our specialty is implicated.3 Our group recently described the impact of state-level legislation on opioid prescribing practices for outpatient plastic surgery procedures.4 Although this law was shown to be successful in decreasing the amount of opioids prescribed, we would ideally seek to determine which patient-specific characteristics indicate whether a patient may require more or fewer opioids before the surgeon writes these prescriptions. In this article, we describe an analysis outlining patient characteristics that were predictors for requiring additional opioid prescriptions following outpatient plastic surgery procedures. Using data derived from all outpatient plastic surgery procedures performed at our institution from June of 2016 through November of 2018, including demographic characteristics, surgery details, and details of both preoperative and postoperative prescriptions, we performed a binary logistic regression analysis to identify any possible predictors of requiring secondary refills of opioids. We found several statistically significant predictors of obtaining secondary opioid prescription refills following outpatient plastic surgery procedures (Table 1). Table 1. - Predictors of Secondary Opioid Prescription following Outpatient Plastic Surgery Procedures Variable OR p Female sex 1.65 0.042 Body mass index (each point increase) 1.02 0.035 Multiple surgical sites 1.02 0.961 Preoperative opioid exposure 2.24 <0.01 Multimodal analgesia prescribed 1.73 <0.01 Abdominoplasty 2.66 0.051 Female sex was found to be associated with increased preponderance of opioid prescription refills postoperatively. However, we largely attribute this to our sample being disproportionately female; other studies have shown that male sex may be related to increased opioid use postoperatively.5 Increasing body mass index also was associated with increased opioid prescription refill. Perhaps most importantly, any exposure to opioids in the 30 days preceding surgery was a predictor of requiring opioid refills postoperatively (OR, 2.2), a finding that has been demonstrated in the orthopedic literature but, to our knowledge, never in plastic surgery patients.5 Prescription of multimodal analgesia at the operative encounter was also predictive of needing postoperative opioid refills. However, there is evidence showing that multimodal pain control in the perioperative period can decrease the use of opioids in the postoperative period, leading us to believe that this finding is more reflective of prescriber anticipating pain needs based on the procedure or the patient rather than nonnarcotic pain medication being a contributor to higher narcotic use. This could also be explained by a population of patients who were started with only nonopioid prescriptions initially and who then subsequently required additional prescription for opioids for further pain control. Our findings that increasing body mass index and preoperative opioid consumption are independently related to increased opioid prescription refills in the postoperative period are the first such reports in plastic surgery patients. This knowledge can be leveraged to assist in decision-making when writing postoperative opioid prescriptions and act as a starting point for future investigation into decreasing opioid use in postoperative patients. ACKNOWLEDGMENTS This project was supported by award UL1TR002733 from the National Center for Advancing Translational Sciences. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center for Advancing Translational Sciences or the National Institutes of Health. DISCLOSURE The authors have no financial interest to declare in relation to the content of this article." @default.
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- W4285586711 date "2022-07-18" @default.
- W4285586711 modified "2023-10-17" @default.
- W4285586711 title "Predictive Factors for Requiring Secondary Opioid Prescriptions following Outpatient Plastic and Reconstructive Surgery" @default.
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- W4285586711 doi "https://doi.org/10.1097/prs.0000000000009422" @default.
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