FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285587476> ?p ?o ?g. }

• W4285587476 abstract "Abstract Lacrimal plug is an effective and widely therapeutic strategy to treat dry eye. However, almost all commercialized plugs are fixed in a certain design and associated with many complications, such as spontaneous plug extrusion, epiphora, and granuloma and cannot be traced in the long‐term. Herein, a simple in situ forming hydrogel is developed as a tracer and degradable lacrimal plug to achieve the best match with the irregular lacrimal passages. In this strategy, methacrylate‐modified silk fibroin (SFMA) is served as a network, and a self‐assembled indocyanine green fluorescence tracer nanoparticle (FTN) is embedded as an indicator to develop the hydrogel plug using visible photo‐crosslinking. This SFMA/FTN hydrogel plug has excellent biocompatibility and biodegradability, which can be noninvasively monitored by near‐infrared light. In vivo tests based on dry eye rabbits show that the SFMA/FTN hydrogel plug can completely block the lacrimal passages and greatly improve the various clinical indicators of dry eye. These results demonstrate that the SFMA/FTN hydrogel is suitable as an injectable and degradable lacrimal plug with a long‐term tracking function. The work offers a new approach to the development of absorbable plugs for the treatment of dry eye." @default.
• W4285587476 created "2022-07-16" @default.
• W4285587476 creator A5008932743 @default.
• W4285587476 creator A5017541508 @default.
• W4285587476 creator A5022786745 @default.
• W4285587476 creator A5029306424 @default.
• W4285587476 creator A5059181133 @default.
• W4285587476 creator A5064726881 @default.
• W4285587476 creator A5074548953 @default.
• W4285587476 creator A5081069826 @default.
• W4285587476 date "2022-07-27" @default.
• W4285587476 modified "2023-10-14" @default.
• W4285587476 title "In Situ Forming Hydrogel as a Tracer and Degradable Lacrimal Plug for Dry Eye Treatment" @default.
• W4285587476 cites W1190101077 @default.
• W4285587476 cites W1203199817 @default.
• W4285587476 cites W1985301413 @default.
• W4285587476 cites W2006119091 @default.
• W4285587476 cites W2009679749 @default.
• W4285587476 cites W2026154976 @default.
• W4285587476 cites W2035753154 @default.
• W4285587476 cites W2052116137 @default.
• W4285587476 cites W2067384539 @default.
• W4285587476 cites W2077543471 @default.
• W4285587476 cites W2147041036 @default.
• W4285587476 cites W2166181129 @default.
• W4285587476 cites W2167343309 @default.
• W4285587476 cites W2178366315 @default.
• W4285587476 cites W2184850868 @default.
• W4285587476 cites W2299003994 @default.
• W4285587476 cites W2329950081 @default.
• W4285587476 cites W2414781026 @default.
• W4285587476 cites W2516087537 @default.
• W4285587476 cites W2532005158 @default.
• W4285587476 cites W2555200685 @default.
• W4285587476 cites W2569131238 @default.
• W4285587476 cites W2608283665 @default.
• W4285587476 cites W2622003939 @default.
• W4285587476 cites W2739359388 @default.
• W4285587476 cites W2739410682 @default.
• W4285587476 cites W2743034468 @default.
• W4285587476 cites W2751025287 @default.
• W4285587476 cites W2766863719 @default.
• W4285587476 cites W2792953143 @default.
• W4285587476 cites W2793182130 @default.
• W4285587476 cites W2793265982 @default.
• W4285587476 cites W2802504186 @default.
• W4285587476 cites W2805543033 @default.
• W4285587476 cites W2895110219 @default.
• W4285587476 cites W2896770336 @default.
• W4285587476 cites W2908795685 @default.
• W4285587476 cites W2910833715 @default.
• W4285587476 cites W2912479316 @default.
• W4285587476 cites W2936143117 @default.
• W4285587476 cites W2944248463 @default.
• W4285587476 cites W2972561894 @default.
• W4285587476 cites W2973044022 @default.
• W4285587476 cites W2983462254 @default.
• W4285587476 cites W2988199981 @default.
• W4285587476 cites W2990722393 @default.
• W4285587476 cites W2993410713 @default.
• W4285587476 cites W2995696514 @default.
• W4285587476 cites W3000396746 @default.
• W4285587476 cites W3005646387 @default.
• W4285587476 cites W3010447146 @default.
• W4285587476 cites W3020731611 @default.
• W4285587476 cites W3024044424 @default.
• W4285587476 cites W3032452236 @default.
• W4285587476 cites W3084953303 @default.
• W4285587476 cites W3086680449 @default.
• W4285587476 cites W3087896330 @default.
• W4285587476 cites W3088875869 @default.
• W4285587476 cites W3090747356 @default.
• W4285587476 cites W3091055257 @default.
• W4285587476 cites W3093199552 @default.
• W4285587476 cites W3098911312 @default.
• W4285587476 cites W3104662334 @default.
• W4285587476 cites W3112937004 @default.
• W4285587476 cites W3133794548 @default.
• W4285587476 cites W3137591091 @default.
• W4285587476 cites W3144584180 @default.
• W4285587476 cites W3158673470 @default.
• W4285587476 cites W3159380695 @default.
• W4285587476 cites W3160518918 @default.
• W4285587476 cites W3163274996 @default.
• W4285587476 cites W3163809020 @default.
• W4285587476 cites W3166037612 @default.
• W4285587476 cites W3172779601 @default.
• W4285587476 cites W3209396341 @default.
• W4285587476 cites W3211474336 @default.
• W4285587476 cites W3216476516 @default.
• W4285587476 cites W356495080 @default.
• W4285587476 cites W4200370166 @default.
• W4285587476 cites W4207074865 @default.
• W4285587476 cites W4210750519 @default.
• W4285587476 doi "https://doi.org/10.1002/adhm.202200678" @default.
• W4285587476 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35841368" @default.
• W4285587476 hasPublicationYear "2022" @default.
• W4285587476 type Work @default.
• W4285587476 citedByCount "6" @default.
• W4285587476 countsByYear W42855874762022 @default.

• next