FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285596502> ?p ?o ?g. }

• W4285596502 endingPage "941" @default.
• W4285596502 startingPage "941" @default.
• W4285596502 abstract "The benefits of remdesivir treatment, with or without co-administration of antibiotics such as azithromycin, are uncertain in COVID-19 pneumonia. The aim of this retrospective single-center study was to assess the effects of remdesivir, with or without azithromycin, on hospital mortality, intensive care unit (ICU) admission, and need of non-invasive ventilation. The clinical records of the COVID-19 patients hospitalized in an Italian ward in March 2021 were analyzed, and data on comorbidities and clinical, radiological, and laboratory presentation of the disease were collected. Among 394 participants (234 M), 173 received remdesivir (43.9%), including 81 with azithromycin (20.5%). Remdesivir recipients were younger, with less comorbidities, and had better PaO2/FiO2 and clinical outcomes, including reduced mortality, but the differences were not independent of covariates. Rates of ICU transferal were 17%, 9%, and 1% in the no remdesivir, remdesivir without azithromycin, and remdesivir/azithromycin groups, respectively. In a stepwise multivariate logistic regression model, remdesivir/azithromycin co-treatment was independently associated with reduced ICU admission (vs remdesivir alone, OR 0.081, 95% CI 0.008–0.789, p = 0.031; vs no remdesivir, OR 0.060, 95% CI 0.007–0.508, p = 0.010). These data suggest that the therapeutical effect of remdesivir in COVID-19 pneumonia may be potentiated by azithromycin. The association between the two drugs should be further investigated." @default.
• W4285596502 created "2022-07-16" @default.
• W4285596502 creator A5001816804 @default.
• W4285596502 creator A5002281246 @default.
• W4285596502 creator A5020973459 @default.
• W4285596502 creator A5037532431 @default.
• W4285596502 creator A5050113285 @default.
• W4285596502 creator A5071238850 @default.
• W4285596502 creator A5074446173 @default.
• W4285596502 creator A5077067347 @default.
• W4285596502 creator A5081130542 @default.
• W4285596502 creator A5082696776 @default.
• W4285596502 date "2022-07-14" @default.
• W4285596502 modified "2023-09-26" @default.
• W4285596502 title "Co-Administration of Remdesivir and Azithromycin May Protect against Intensive Care Unit Admission in COVID-19 Pneumonia Requiring Hospitalization: A Real-Life Observational Study" @default.
• W4285596502 cites W3022973194 @default.
• W4285596502 cites W3027630905 @default.
• W4285596502 cites W3080857519 @default.
• W4285596502 cites W3081368778 @default.
• W4285596502 cites W3081745349 @default.
• W4285596502 cites W3087825975 @default.
• W4285596502 cites W3094298843 @default.
• W4285596502 cites W3097673122 @default.
• W4285596502 cites W3102966306 @default.
• W4285596502 cites W3126379194 @default.
• W4285596502 cites W3135230718 @default.
• W4285596502 cites W3135260263 @default.
• W4285596502 cites W3135714043 @default.
• W4285596502 cites W3137806851 @default.
• W4285596502 cites W3152592043 @default.
• W4285596502 cites W3161817473 @default.
• W4285596502 cites W3164764041 @default.
• W4285596502 cites W3164995039 @default.
• W4285596502 cites W3173485005 @default.
• W4285596502 cites W3175097333 @default.
• W4285596502 cites W3193128044 @default.
• W4285596502 cites W3194016737 @default.
• W4285596502 cites W3194480126 @default.
• W4285596502 cites W3196439811 @default.
• W4285596502 cites W3209943140 @default.
• W4285596502 cites W3213715446 @default.
• W4285596502 cites W3216810195 @default.
• W4285596502 cites W3217529278 @default.
• W4285596502 cites W4200206478 @default.
• W4285596502 cites W4205677903 @default.
• W4285596502 cites W4214625822 @default.
• W4285596502 cites W4225313493 @default.
• W4285596502 cites W4225660133 @default.
• W4285596502 cites W4280611318 @default.
• W4285596502 cites W4282584612 @default.
• W4285596502 doi "https://doi.org/10.3390/antibiotics11070941" @default.
• W4285596502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35884195" @default.
• W4285596502 hasPublicationYear "2022" @default.
• W4285596502 type Work @default.
• W4285596502 citedByCount "3" @default.
• W4285596502 countsByYear W42855965022022 @default.
• W4285596502 countsByYear W42855965022023 @default.
• W4285596502 crossrefType "journal-article" @default.
• W4285596502 hasAuthorship W4285596502A5001816804 @default.
• W4285596502 hasAuthorship W4285596502A5002281246 @default.
• W4285596502 hasAuthorship W4285596502A5020973459 @default.
• W4285596502 hasAuthorship W4285596502A5037532431 @default.
• W4285596502 hasAuthorship W4285596502A5050113285 @default.
• W4285596502 hasAuthorship W4285596502A5071238850 @default.
• W4285596502 hasAuthorship W4285596502A5074446173 @default.
• W4285596502 hasAuthorship W4285596502A5077067347 @default.
• W4285596502 hasAuthorship W4285596502A5081130542 @default.
• W4285596502 hasAuthorship W4285596502A5082696776 @default.
• W4285596502 hasBestOaLocation W42855965021 @default.
• W4285596502 hasConcept C126322002 @default.
• W4285596502 hasConcept C151956035 @default.
• W4285596502 hasConcept C167135981 @default.
• W4285596502 hasConcept C177713679 @default.
• W4285596502 hasConcept C194828623 @default.
• W4285596502 hasConcept C2776376669 @default.
• W4285596502 hasConcept C2777914695 @default.
• W4285596502 hasConcept C2778907293 @default.
• W4285596502 hasConcept C501593827 @default.
• W4285596502 hasConcept C71924100 @default.
• W4285596502 hasConcept C86803240 @default.
• W4285596502 hasConcept C89423630 @default.
• W4285596502 hasConceptScore W4285596502C126322002 @default.
• W4285596502 hasConceptScore W4285596502C151956035 @default.
• W4285596502 hasConceptScore W4285596502C167135981 @default.
• W4285596502 hasConceptScore W4285596502C177713679 @default.
• W4285596502 hasConceptScore W4285596502C194828623 @default.
• W4285596502 hasConceptScore W4285596502C2776376669 @default.
• W4285596502 hasConceptScore W4285596502C2777914695 @default.
• W4285596502 hasConceptScore W4285596502C2778907293 @default.
• W4285596502 hasConceptScore W4285596502C501593827 @default.
• W4285596502 hasConceptScore W4285596502C71924100 @default.
• W4285596502 hasConceptScore W4285596502C86803240 @default.
• W4285596502 hasConceptScore W4285596502C89423630 @default.
• W4285596502 hasIssue "7" @default.
• W4285596502 hasLocation W42855965021 @default.
• W4285596502 hasLocation W42855965022 @default.
• W4285596502 hasLocation W42855965023 @default.
• W4285596502 hasOpenAccess W4285596502 @default.

• next