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- W4285607687 abstract "Vitamin D plays an important role in mineral and bone homeostasis, immune responses, cardiovascular function and keratinocyte proliferation and differentiation. Vitamin D performs most of its functions by binding to vitamin D receptors (VDR), which interact with other intracellular signaling pathways to regulate bone metabolism, inflammation, immunity, cell cycle progression and apoptosis. Autophagy is a basic stress response in yeast, plants and mammals, and plays a critical role in maintaining optimal functional states at the level of cells and organs. Vitamin D/VDR plays an anti-infection role via inducing and regulating autophagy.维生素D在钙磷代谢中起重要作用，同时具有调节机体免疫功能、心血管功能及角质形成细胞增殖和分化的能力。维生素D的大部分功能是通过与维生素D受体(vitamin receptor，VDR)结合后实现的，VDR信号通路与其他细胞内信号通路相互作用，从而调节骨代谢、炎症反应、免疫反应、细胞周期进程和凋亡。细胞自噬在酵母、植物和哺乳动物中是一种基本的应激反应，对维持细胞和器官的最佳功能状态起至关重要的作用。维生素D/VDR通过诱导和调节自噬发挥抗感染的作用。." @default.
- W4285607687 created "2022-07-16" @default.
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- W4285607687 date "2022-06-28" @default.
- W4285607687 modified "2023-10-18" @default.
- W4285607687 title "Vitamin D/vitamin D receptor, autophagy, and infection." @default.
- W4285607687 doi "https://doi.org/10.11817/j.issn.1672-7347.2022.210556" @default.
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