Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285675917> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4285675917 endingPage "81" @default.
- W4285675917 startingPage "71" @default.
- W4285675917 abstract "Non alcoholic Steatohepatitis (NASH) is part of a group of conditions called Non-Alcoholic Fatty Liver Diseases(NAFLD) where it is a chronic disease, which defined after elimination other causes of fatty liver, such as excessivealcohol consumption and other causes of chronic liver diseases. NASH is fatty liver disease which characterized byballooning of hepatocyte and lobular inflammation with or without fibrosis. Histopathology diagnose on NASH can bedefined by performing liver biopsy. The purpose of liver biopsy is to define level and degree of the disease. Cluster ofDifferentiation (CD) 44 is a transmembrane glycoprotein receptor which located on the surface of macrophage cells,lymphocytes and endothelial cells. In studies which conducted on mice and humans, showed that CD44 playsimportant role in the progression of NASH. CD44 regulates inflammation of adipose tissue and liver. CD44 ispresumed as a marker which increase macrophage infiltration and other inflammatory cells on liver. This processleads to ultimate increment on insulin resistance and fatty liver. Deficiency was discovered on mice which injectedwith methionine and choline deficiency diet (MCDD). CD44 is associated with preventive method to prevent livercomplication by reducing macrophage or monocyte and as well as neutrophil accumulation in liver which wasevaluated through reducing numbers of inflammatory focus, expression of inflammatory cytokines: tumor necrosisfactor α (TNFα), interleukin (IL) -1B and nitric oxide synthesis (iNOS), and pro-inflammatory types of macrophage. Inobese patients, number of CD44 is predicted to be increasing." @default.
- W4285675917 created "2022-07-17" @default.
- W4285675917 creator A5037802721 @default.
- W4285675917 creator A5058643715 @default.
- W4285675917 creator A5088732476 @default.
- W4285675917 date "2020-05-01" @default.
- W4285675917 modified "2023-10-06" @default.
- W4285675917 title "Role of CD44 in Non-Alcoholic Steatohepatitis (NASH) Progressivity" @default.
- W4285675917 doi "https://doi.org/10.55816/mpi.v29i2.415" @default.
- W4285675917 hasPublicationYear "2020" @default.
- W4285675917 type Work @default.
- W4285675917 citedByCount "0" @default.
- W4285675917 crossrefType "journal-article" @default.
- W4285675917 hasAuthorship W4285675917A5037802721 @default.
- W4285675917 hasAuthorship W4285675917A5058643715 @default.
- W4285675917 hasAuthorship W4285675917A5088732476 @default.
- W4285675917 hasBestOaLocation W42856759171 @default.
- W4285675917 hasConcept C126322002 @default.
- W4285675917 hasConcept C134018914 @default.
- W4285675917 hasConcept C142724271 @default.
- W4285675917 hasConcept C202751555 @default.
- W4285675917 hasConcept C2775858924 @default.
- W4285675917 hasConcept C2775934546 @default.
- W4285675917 hasConcept C2776914184 @default.
- W4285675917 hasConcept C2777075537 @default.
- W4285675917 hasConcept C2777214474 @default.
- W4285675917 hasConcept C2777766500 @default.
- W4285675917 hasConcept C2778772119 @default.
- W4285675917 hasConcept C2778904781 @default.
- W4285675917 hasConcept C2779102576 @default.
- W4285675917 hasConcept C2779134260 @default.
- W4285675917 hasConcept C2779244956 @default.
- W4285675917 hasConcept C2779478299 @default.
- W4285675917 hasConcept C2780559512 @default.
- W4285675917 hasConcept C55493867 @default.
- W4285675917 hasConcept C71924100 @default.
- W4285675917 hasConcept C86803240 @default.
- W4285675917 hasConceptScore W4285675917C126322002 @default.
- W4285675917 hasConceptScore W4285675917C134018914 @default.
- W4285675917 hasConceptScore W4285675917C142724271 @default.
- W4285675917 hasConceptScore W4285675917C202751555 @default.
- W4285675917 hasConceptScore W4285675917C2775858924 @default.
- W4285675917 hasConceptScore W4285675917C2775934546 @default.
- W4285675917 hasConceptScore W4285675917C2776914184 @default.
- W4285675917 hasConceptScore W4285675917C2777075537 @default.
- W4285675917 hasConceptScore W4285675917C2777214474 @default.
- W4285675917 hasConceptScore W4285675917C2777766500 @default.
- W4285675917 hasConceptScore W4285675917C2778772119 @default.
- W4285675917 hasConceptScore W4285675917C2778904781 @default.
- W4285675917 hasConceptScore W4285675917C2779102576 @default.
- W4285675917 hasConceptScore W4285675917C2779134260 @default.
- W4285675917 hasConceptScore W4285675917C2779244956 @default.
- W4285675917 hasConceptScore W4285675917C2779478299 @default.
- W4285675917 hasConceptScore W4285675917C2780559512 @default.
- W4285675917 hasConceptScore W4285675917C55493867 @default.
- W4285675917 hasConceptScore W4285675917C71924100 @default.
- W4285675917 hasConceptScore W4285675917C86803240 @default.
- W4285675917 hasIssue "2" @default.
- W4285675917 hasLocation W42856759171 @default.
- W4285675917 hasOpenAccess W4285675917 @default.
- W4285675917 hasPrimaryLocation W42856759171 @default.
- W4285675917 hasRelatedWork W141267622 @default.
- W4285675917 hasRelatedWork W16630661 @default.
- W4285675917 hasRelatedWork W1934590957 @default.
- W4285675917 hasRelatedWork W1975223846 @default.
- W4285675917 hasRelatedWork W2014718725 @default.
- W4285675917 hasRelatedWork W2026169386 @default.
- W4285675917 hasRelatedWork W2107697606 @default.
- W4285675917 hasRelatedWork W2885432910 @default.
- W4285675917 hasRelatedWork W3112437899 @default.
- W4285675917 hasRelatedWork W3215462966 @default.
- W4285675917 hasVolume "29" @default.
- W4285675917 isParatext "false" @default.
- W4285675917 isRetracted "false" @default.
- W4285675917 workType "article" @default.