Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285676530> ?p ?o ?g. }
- W4285676530 abstract "Abstract The citrate carrier (CIC) is an integral protein of the inner mitochondrial membrane which catalyzes the efflux of mitochondrial citrate (or other tricarboxylates) in exchange with a cytosolic anion represented by a tricarboxylate or a dicarboxylate or phosphoenolpyruvate. In this way, the CIC provides the cytosol with citrate which is involved in many metabolic reactions. Several studies have been carried out over the years on the structure, function and regulation of this metabolite carrier protein both in mammals and in many other organisms. A lot of data on the characteristics of this protein have therefore accumulated over time thereby leading to a complex framework of metabolic and physiological implications connected to the CIC function. In this review, we critically analyze these data starting from the multiple roles played by the mitochondrial CIC in many cellular processes and then examining the regulation of its activity in different nutritional and hormonal states. Finally, the metabolic significance of the citrate flux, mediated by the CIC, across distinct subcellular compartments is also discussed." @default.
- W4285676530 created "2022-07-17" @default.
- W4285676530 creator A5042358406 @default.
- W4285676530 creator A5050663523 @default.
- W4285676530 creator A5089132034 @default.
- W4285676530 date "2022-07-17" @default.
- W4285676530 modified "2023-10-09" @default.
- W4285676530 title "Multiple roles played by the mitochondrial citrate carrier in cellular metabolism and physiology" @default.
- W4285676530 cites W1486858995 @default.
- W4285676530 cites W1499384204 @default.
- W4285676530 cites W1513562133 @default.
- W4285676530 cites W1526191506 @default.
- W4285676530 cites W1526845682 @default.
- W4285676530 cites W1530768309 @default.
- W4285676530 cites W1531638822 @default.
- W4285676530 cites W1540221097 @default.
- W4285676530 cites W1552151239 @default.
- W4285676530 cites W1566163765 @default.
- W4285676530 cites W1572077460 @default.
- W4285676530 cites W1595308056 @default.
- W4285676530 cites W1657478053 @default.
- W4285676530 cites W174750072 @default.
- W4285676530 cites W1760703658 @default.
- W4285676530 cites W1850309226 @default.
- W4285676530 cites W1967436314 @default.
- W4285676530 cites W1971413372 @default.
- W4285676530 cites W1972451805 @default.
- W4285676530 cites W1975286879 @default.
- W4285676530 cites W1978076094 @default.
- W4285676530 cites W1978294917 @default.
- W4285676530 cites W1990312478 @default.
- W4285676530 cites W1992055378 @default.
- W4285676530 cites W1992209802 @default.
- W4285676530 cites W1992408933 @default.
- W4285676530 cites W1993283659 @default.
- W4285676530 cites W1993540067 @default.
- W4285676530 cites W1994930939 @default.
- W4285676530 cites W2003066185 @default.
- W4285676530 cites W2003859301 @default.
- W4285676530 cites W2005190612 @default.
- W4285676530 cites W2005602228 @default.
- W4285676530 cites W2009636878 @default.
- W4285676530 cites W2022228039 @default.
- W4285676530 cites W2024988671 @default.
- W4285676530 cites W2026597706 @default.
- W4285676530 cites W2030548279 @default.
- W4285676530 cites W2036848107 @default.
- W4285676530 cites W2040023013 @default.
- W4285676530 cites W2040759448 @default.
- W4285676530 cites W2041295662 @default.
- W4285676530 cites W2044100362 @default.
- W4285676530 cites W2046005912 @default.
- W4285676530 cites W2049044905 @default.
- W4285676530 cites W2051102910 @default.
- W4285676530 cites W2056113150 @default.
- W4285676530 cites W2057934502 @default.
- W4285676530 cites W2059210054 @default.
- W4285676530 cites W2060313074 @default.
- W4285676530 cites W2063004731 @default.
- W4285676530 cites W2070482948 @default.
- W4285676530 cites W2075945722 @default.
- W4285676530 cites W2078862746 @default.
- W4285676530 cites W2079467363 @default.
- W4285676530 cites W2087996596 @default.
- W4285676530 cites W2096501714 @default.
- W4285676530 cites W2097010303 @default.
- W4285676530 cites W2106762395 @default.
- W4285676530 cites W2121048884 @default.
- W4285676530 cites W2123190744 @default.
- W4285676530 cites W2124769976 @default.
- W4285676530 cites W2128469364 @default.
- W4285676530 cites W2133452708 @default.
- W4285676530 cites W2135766195 @default.
- W4285676530 cites W2136169891 @default.
- W4285676530 cites W2136454890 @default.
- W4285676530 cites W2138240713 @default.
- W4285676530 cites W2138709778 @default.
- W4285676530 cites W2138840469 @default.
- W4285676530 cites W2142079020 @default.
- W4285676530 cites W2144575277 @default.
- W4285676530 cites W2147248422 @default.
- W4285676530 cites W2160284636 @default.
- W4285676530 cites W2322803810 @default.
- W4285676530 cites W2324601854 @default.
- W4285676530 cites W2598956467 @default.
- W4285676530 cites W2800650242 @default.
- W4285676530 cites W2905704278 @default.
- W4285676530 cites W3018107162 @default.
- W4285676530 cites W3041551793 @default.
- W4285676530 cites W3048846827 @default.
- W4285676530 cites W3049430695 @default.
- W4285676530 cites W3081483335 @default.
- W4285676530 cites W3105639016 @default.
- W4285676530 cites W3111156303 @default.
- W4285676530 cites W3120660874 @default.
- W4285676530 cites W3122767802 @default.
- W4285676530 cites W3126825720 @default.
- W4285676530 cites W3159338232 @default.
- W4285676530 cites W3165482261 @default.
- W4285676530 cites W3189035302 @default.