FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285676812> ?p ?o ?g. }

• W4285676812 abstract "Methamphetamine use is surging globally as a cause of morbidity and mortality. Treatment is typically sought in early abstinence, when craving and depressive symptoms are intense, contributing to relapse and poor outcomes. To advance an understanding of this problem and identify therapeutic targets, we conducted a retrospective analysis of brain structure in 89 adults with Methamphetamine Use Disorder who were in early abstinence and 89 healthy controls. Unlike most prior research, the participants did not significantly differ in age, sex and recent use of alcohol and tobacco (p-values ≥ 0.400). We analysed thickness across the entire cerebral cortex by fitting a general linear model to identify differences between groups. Follow-up regressions were performed to determine whether cortical thickness in regions showing group differences was related to craving, measured on a visual analogue scale, or to the Beck Depression Inventory score. Participants in early methamphetamine abstinence (M ± SD = 22.1 ± 25.6 days) exhibited thinner cortex in clusters within bilateral frontal, parietal, temporal, insular, and right cingulate cortices relative to controls (p-values < 0.001, corrected for multiple comparisons). Unlike craving (β = 0.007, p = 0.947), depressive symptoms were positively correlated with cortical thickness across clusters (β = 0.239, p = 0.030) and with thickness in the anterior cingulate cluster (β = 0.246, p = 0.027) in the methamphetamine-dependent group. Inasmuch as anterior cingulate pathology predicts response to antidepressants for Major Depressive Disorder, cingulate structure may also identify patients with Methamphetamine Use Disorder who can benefit from antidepressant medication." @default.
• W4285676812 created "2022-07-17" @default.
• W4285676812 creator A5008949967 @default.
• W4285676812 creator A5019337347 @default.
• W4285676812 creator A5028618881 @default.
• W4285676812 creator A5030381992 @default.
• W4285676812 creator A5030520972 @default.
• W4285676812 creator A5035218180 @default.
• W4285676812 date "2022-07-17" @default.
• W4285676812 modified "2023-10-16" @default.
• W4285676812 title "Cortical thickness and related depressive symptoms in early abstinence from chronic methamphetamine use" @default.
• W4285676812 cites W1943082353 @default.
• W4285676812 cites W1986528761 @default.
• W4285676812 cites W1989816896 @default.
• W4285676812 cites W1991257812 @default.
• W4285676812 cites W1992861430 @default.
• W4285676812 cites W1995522022 @default.
• W4285676812 cites W2009786630 @default.
• W4285676812 cites W2020680049 @default.
• W4285676812 cites W2020743147 @default.
• W4285676812 cites W2037557484 @default.
• W4285676812 cites W2046130760 @default.
• W4285676812 cites W2050431379 @default.
• W4285676812 cites W2052021683 @default.
• W4285676812 cites W2053734916 @default.
• W4285676812 cites W2085864665 @default.
• W4285676812 cites W2093894007 @default.
• W4285676812 cites W2094788831 @default.
• W4285676812 cites W2117364601 @default.
• W4285676812 cites W2117792476 @default.
• W4285676812 cites W2123523993 @default.
• W4285676812 cites W2124878104 @default.
• W4285676812 cites W2143742215 @default.
• W4285676812 cites W2148484180 @default.
• W4285676812 cites W2151721316 @default.
• W4285676812 cites W2154345916 @default.
• W4285676812 cites W2168118702 @default.
• W4285676812 cites W2189658019 @default.
• W4285676812 cites W2340300692 @default.
• W4285676812 cites W2346576232 @default.
• W4285676812 cites W2526484688 @default.
• W4285676812 cites W2588307613 @default.
• W4285676812 cites W2755245022 @default.
• W4285676812 cites W2765884802 @default.
• W4285676812 cites W2776130467 @default.
• W4285676812 cites W2792327341 @default.
• W4285676812 cites W2802380795 @default.
• W4285676812 cites W2887351119 @default.
• W4285676812 cites W2898156245 @default.
• W4285676812 cites W2899568001 @default.
• W4285676812 cites W2911135784 @default.
• W4285676812 cites W2942772596 @default.
• W4285676812 cites W2950086191 @default.
• W4285676812 cites W2962839503 @default.
• W4285676812 cites W2978085759 @default.
• W4285676812 cites W2982944944 @default.
• W4285676812 cites W2983572746 @default.
• W4285676812 cites W2995739647 @default.
• W4285676812 cites W3003860245 @default.
• W4285676812 cites W3008383376 @default.
• W4285676812 cites W3010839704 @default.
• W4285676812 cites W3014162834 @default.
• W4285676812 cites W3024910468 @default.
• W4285676812 cites W3048231871 @default.
• W4285676812 cites W3091802322 @default.
• W4285676812 cites W3118521719 @default.
• W4285676812 cites W3145856311 @default.
• W4285676812 cites W3194324131 @default.
• W4285676812 cites W3200148840 @default.
• W4285676812 cites W4243177274 @default.
• W4285676812 doi "https://doi.org/10.1111/adb.13205" @default.
• W4285676812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36001419" @default.
• W4285676812 hasPublicationYear "2022" @default.
• W4285676812 type Work @default.
• W4285676812 citedByCount "0" @default.
• W4285676812 crossrefType "journal-article" @default.
• W4285676812 hasAuthorship W4285676812A5008949967 @default.
• W4285676812 hasAuthorship W4285676812A5019337347 @default.
• W4285676812 hasAuthorship W4285676812A5028618881 @default.
• W4285676812 hasAuthorship W4285676812A5030381992 @default.
• W4285676812 hasAuthorship W4285676812A5030520972 @default.
• W4285676812 hasAuthorship W4285676812A5035218180 @default.
• W4285676812 hasConcept C118552586 @default.
• W4285676812 hasConcept C126322002 @default.
• W4285676812 hasConcept C139719470 @default.
• W4285676812 hasConcept C15744967 @default.
• W4285676812 hasConcept C162324750 @default.
• W4285676812 hasConcept C169900460 @default.
• W4285676812 hasConcept C2776867660 @default.
• W4285676812 hasConcept C2778402161 @default.
• W4285676812 hasConcept C2779541405 @default.
• W4285676812 hasConcept C2779631380 @default.
• W4285676812 hasConcept C2780051608 @default.
• W4285676812 hasConcept C2780376393 @default.
• W4285676812 hasConcept C2780687700 @default.
• W4285676812 hasConcept C2781210436 @default.
• W4285676812 hasConcept C48856860 @default.
• W4285676812 hasConcept C529278444 @default.
• W4285676812 hasConcept C558461103 @default.
• W4285676812 hasConcept C70410870 @default.

• next