Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285804906> ?p ?o ?g. }
- W4285804906 endingPage "23889" @default.
- W4285804906 startingPage "23875" @default.
- W4285804906 abstract "Nanoencapsulation with safe materials improves delivery, stability, and activity of bioactive components. We report a novel safe, and effective method for the development of encapsulated antimicrobial essential oils (EO) for topical creams and gels. The method developed features three aspects that, to our knowledge, had not been previously demonstrated: (1) use of novel liposomes (LPs) to encapsulate EOs, (2) use of the EOs to replace synthetic organic solvents that are potentially toxic and/or leave harmful residues, and (3) an encapsulation process at temperatures below the boiling point of water. The LPs were made from soy lecithin, phytosterol, and α-tocopherol (vitamin E) that were synthesized using the EOs as the solvent. The liposomes were converted to nanoliposomes (NLPs) through a series of sonication, homogenization, and extrusion steps. Transmission electron microscopy indicated that the NLPs alone and nanoliposome encapsulated EOs (NLP-EOs) were spherical in shape with sizes ranging between 50 and 115 nm diameter and with negative zeta potentials ranging from -34 to -43 mV. There was no significant heavy metal contamination [As, Pb, Cd, Hg] based on inductively coupled plasma (ICP) mass spectrometry MS analyses. Nearly complete EO encapsulation (95% encapsulation efficiency) was achieved and confirmed by GC/MS. Three of the NLP-EOs made of various essential oils were used to make topical formulations (cream and gel) which exhibited antimicrobial activities against Escherichia coli (Gram negative) and Bacillus subtilis (Gram positive) bacteria. The creams with NLP-EOs were as active against the two bacteria in the antimicrobial assays as the conventional antibiotic Kanamycin that was used as positive control." @default.
- W4285804906 created "2022-07-19" @default.
- W4285804906 creator A5029859931 @default.
- W4285804906 creator A5038757746 @default.
- W4285804906 creator A5045642330 @default.
- W4285804906 date "2022-06-27" @default.
- W4285804906 modified "2023-09-23" @default.
- W4285804906 title "Development of Biodegradable/Biocompatible Nanoliposome-Encapsulated Antimicrobial Essential Oils for Topical Creams and Gels" @default.
- W4285804906 cites W1515206981 @default.
- W4285804906 cites W1626053442 @default.
- W4285804906 cites W1843650615 @default.
- W4285804906 cites W1966161984 @default.
- W4285804906 cites W1970710265 @default.
- W4285804906 cites W1972334980 @default.
- W4285804906 cites W1976358161 @default.
- W4285804906 cites W1976656293 @default.
- W4285804906 cites W1977204106 @default.
- W4285804906 cites W1983014516 @default.
- W4285804906 cites W1983218403 @default.
- W4285804906 cites W1983316742 @default.
- W4285804906 cites W1986329432 @default.
- W4285804906 cites W1987843843 @default.
- W4285804906 cites W1990926854 @default.
- W4285804906 cites W1991390001 @default.
- W4285804906 cites W2000758651 @default.
- W4285804906 cites W2004870695 @default.
- W4285804906 cites W2009666276 @default.
- W4285804906 cites W2009974403 @default.
- W4285804906 cites W2016711291 @default.
- W4285804906 cites W2020702188 @default.
- W4285804906 cites W2026890893 @default.
- W4285804906 cites W2028349699 @default.
- W4285804906 cites W2029599234 @default.
- W4285804906 cites W2036623928 @default.
- W4285804906 cites W2039060982 @default.
- W4285804906 cites W2041504874 @default.
- W4285804906 cites W2046604196 @default.
- W4285804906 cites W2051925512 @default.
- W4285804906 cites W2054177915 @default.
- W4285804906 cites W2054760430 @default.
- W4285804906 cites W2058052554 @default.
- W4285804906 cites W2058986130 @default.
- W4285804906 cites W2060098112 @default.
- W4285804906 cites W2065098180 @default.
- W4285804906 cites W2070361637 @default.
- W4285804906 cites W2075986899 @default.
- W4285804906 cites W2095183982 @default.
- W4285804906 cites W2097603366 @default.
- W4285804906 cites W2099412187 @default.
- W4285804906 cites W2104982872 @default.
- W4285804906 cites W2105018278 @default.
- W4285804906 cites W2107205997 @default.
- W4285804906 cites W2107910518 @default.
- W4285804906 cites W2110837175 @default.
- W4285804906 cites W2112054219 @default.
- W4285804906 cites W2117097206 @default.
- W4285804906 cites W2117799621 @default.
- W4285804906 cites W2120584852 @default.
- W4285804906 cites W2122910156 @default.
- W4285804906 cites W2123152369 @default.
- W4285804906 cites W2126405942 @default.
- W4285804906 cites W2130039843 @default.
- W4285804906 cites W2139587688 @default.
- W4285804906 cites W2152704118 @default.
- W4285804906 cites W2158921004 @default.
- W4285804906 cites W2164168857 @default.
- W4285804906 cites W2167691424 @default.
- W4285804906 cites W2167916315 @default.
- W4285804906 cites W2185564569 @default.
- W4285804906 cites W2293145628 @default.
- W4285804906 cites W2306788901 @default.
- W4285804906 cites W2460460441 @default.
- W4285804906 cites W2514083269 @default.
- W4285804906 cites W2562627217 @default.
- W4285804906 cites W2573043361 @default.
- W4285804906 cites W2573540928 @default.
- W4285804906 cites W2575232237 @default.
- W4285804906 cites W2599276599 @default.
- W4285804906 cites W2727899900 @default.
- W4285804906 cites W2757268196 @default.
- W4285804906 cites W3013259145 @default.
- W4285804906 cites W3115389943 @default.
- W4285804906 cites W3166884470 @default.
- W4285804906 cites W368181379 @default.
- W4285804906 cites W4236601091 @default.
- W4285804906 cites W4244322202 @default.
- W4285804906 cites W4250840928 @default.
- W4285804906 cites W4252297210 @default.
- W4285804906 cites W4256694311 @default.
- W4285804906 doi "https://doi.org/10.1021/acsomega.2c02594" @default.
- W4285804906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35847299" @default.
- W4285804906 hasPublicationYear "2022" @default.
- W4285804906 type Work @default.
- W4285804906 citedByCount "0" @default.
- W4285804906 crossrefType "journal-article" @default.
- W4285804906 hasAuthorship W4285804906A5029859931 @default.
- W4285804906 hasAuthorship W4285804906A5038757746 @default.
- W4285804906 hasAuthorship W4285804906A5045642330 @default.