Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285812984> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4285812984 endingPage "11260" @default.
- W4285812984 startingPage "11260" @default.
- W4285812984 abstract "The study investigated the effect of ethyl acetate pod extract of Tetrapleura tetraptera on biochemical markers of liver damage, in vivo and in vitro antioxidant properties using acetaminophen-injured female rats as model. Thirty-five (35) rats assigned into seven groups (A-G) of five rats per group were used for the study. Rats in groups C, D, E and F were pretreated with 100, 200, 400 and 200 mg/kg of the extract while group G rats received Silymarin (100 mg/kg). Distilled water (10 ml/kg) was administered to groups A and B rats. All pretreatments were via the oral route and lasted for seven days. Following pretreatments, acetaminophen (2000 mg/kg) was used to induce liver injury in groups B, C, D, E and G while rats in group A served as normal control. Blood samples were collected 48 h post acetaminophen administration for analyses of the following parameters: Alanine aminotransferase (ALT), alkaline phosphatase (ALP), serum bilirubin, reduced glutathione and superoxide dismutase. Liver tissues were collected for histopathology studies. In vitro antioxidant profile of the extract was evaluated. Results indicated decreases in the activities of ALT and ALP of the extract-treated groups compared to the negative control group. The liver section of the rats treated with 400 mg/kg of the extract showed no lesions and was comparable to that of the normal control rats. The in vivo and in vitro antioxidant activities were in dose and concentration-dependent manner respectively. It was concluded that Tetrapleura tetraptera ethyl acetate extract possesses both hepatoprotective and antioxidant properties." @default.
- W4285812984 created "2022-07-19" @default.
- W4285812984 creator A5044473170 @default.
- W4285812984 creator A5054527313 @default.
- W4285812984 creator A5059498883 @default.
- W4285812984 date "2022-06-06" @default.
- W4285812984 modified "2023-10-14" @default.
- W4285812984 title "Tetrapleura tetraptera ethylacetate pod extract and its biochemical effects on acetaminophen-induced hepatotoxic female rat" @default.
- W4285812984 doi "https://doi.org/10.55779/nsb14211260" @default.
- W4285812984 hasPublicationYear "2022" @default.
- W4285812984 type Work @default.
- W4285812984 citedByCount "0" @default.
- W4285812984 crossrefType "journal-article" @default.
- W4285812984 hasAuthorship W4285812984A5044473170 @default.
- W4285812984 hasAuthorship W4285812984A5054527313 @default.
- W4285812984 hasAuthorship W4285812984A5059498883 @default.
- W4285812984 hasBestOaLocation W42858129841 @default.
- W4285812984 hasConcept C126322002 @default.
- W4285812984 hasConcept C150903083 @default.
- W4285812984 hasConcept C160160445 @default.
- W4285812984 hasConcept C181199279 @default.
- W4285812984 hasConcept C185592680 @default.
- W4285812984 hasConcept C207001950 @default.
- W4285812984 hasConcept C2775838275 @default.
- W4285812984 hasConcept C2776637226 @default.
- W4285812984 hasConcept C2777513400 @default.
- W4285812984 hasConcept C2778004101 @default.
- W4285812984 hasConcept C2778722691 @default.
- W4285812984 hasConcept C2779429693 @default.
- W4285812984 hasConcept C2779858419 @default.
- W4285812984 hasConcept C43617362 @default.
- W4285812984 hasConcept C538909803 @default.
- W4285812984 hasConcept C55493867 @default.
- W4285812984 hasConcept C556039675 @default.
- W4285812984 hasConcept C71924100 @default.
- W4285812984 hasConcept C86803240 @default.
- W4285812984 hasConcept C98274493 @default.
- W4285812984 hasConceptScore W4285812984C126322002 @default.
- W4285812984 hasConceptScore W4285812984C150903083 @default.
- W4285812984 hasConceptScore W4285812984C160160445 @default.
- W4285812984 hasConceptScore W4285812984C181199279 @default.
- W4285812984 hasConceptScore W4285812984C185592680 @default.
- W4285812984 hasConceptScore W4285812984C207001950 @default.
- W4285812984 hasConceptScore W4285812984C2775838275 @default.
- W4285812984 hasConceptScore W4285812984C2776637226 @default.
- W4285812984 hasConceptScore W4285812984C2777513400 @default.
- W4285812984 hasConceptScore W4285812984C2778004101 @default.
- W4285812984 hasConceptScore W4285812984C2778722691 @default.
- W4285812984 hasConceptScore W4285812984C2779429693 @default.
- W4285812984 hasConceptScore W4285812984C2779858419 @default.
- W4285812984 hasConceptScore W4285812984C43617362 @default.
- W4285812984 hasConceptScore W4285812984C538909803 @default.
- W4285812984 hasConceptScore W4285812984C55493867 @default.
- W4285812984 hasConceptScore W4285812984C556039675 @default.
- W4285812984 hasConceptScore W4285812984C71924100 @default.
- W4285812984 hasConceptScore W4285812984C86803240 @default.
- W4285812984 hasConceptScore W4285812984C98274493 @default.
- W4285812984 hasIssue "2" @default.
- W4285812984 hasLocation W42858129841 @default.
- W4285812984 hasOpenAccess W4285812984 @default.
- W4285812984 hasPrimaryLocation W42858129841 @default.
- W4285812984 hasRelatedWork W1970628566 @default.
- W4285812984 hasRelatedWork W2048660546 @default.
- W4285812984 hasRelatedWork W2052185098 @default.
- W4285812984 hasRelatedWork W2068520623 @default.
- W4285812984 hasRelatedWork W2114534540 @default.
- W4285812984 hasRelatedWork W2782836743 @default.
- W4285812984 hasRelatedWork W306408303 @default.
- W4285812984 hasRelatedWork W1872247900 @default.
- W4285812984 hasRelatedWork W2044231188 @default.
- W4285812984 hasRelatedWork W2550525474 @default.
- W4285812984 hasVolume "14" @default.
- W4285812984 isParatext "false" @default.
- W4285812984 isRetracted "false" @default.
- W4285812984 workType "article" @default.