Matches in SemOpenAlex for { <https://semopenalex.org/work/W4285820380> ?p ?o ?g. }
- W4285820380 endingPage "195" @default.
- W4285820380 startingPage "165" @default.
- W4285820380 abstract "The search for new drugs from natural products with bioactive properties has increased significantly in the last decade, after the drop in discoveries using chemical synthesis. Following this trend, the use of metabolomic techniques has been intensified both to discover new metabolites in complex matrices (global analysis), as well as to understand the cell's physiological changes of a specific metabolite (target analysis). Advances in the development of metabolomic technologies, as analytical techniques and bioinformatic tools, have enabled a more effective understanding of complex biological matrices, by applying analytical techniques, such as nuclear magnetic resonance, and gas and liquid chromatography coupled to mass spectrometry, thus facilitating the discovery of new bioactive compounds. Due to the complexity of metabolomics data sets, chemometric techniques have aided the identification of bioactive compounds in samples from different origins, allowing the development of new pharmaceutical products on a more rational basis. In this sense, this chapter focuses on how metabolomics has aided in the discovery of bioactive compounds using corn, propolis, and algae as biological models of study, as they have been recognized as sources of natural products with pharmaceutical potential, such as isoquinolinic alkaloids and sterols, among others." @default.
- W4285820380 created "2022-07-19" @default.
- W4285820380 creator A5019176805 @default.
- W4285820380 creator A5052423735 @default.
- W4285820380 creator A5053051965 @default.
- W4285820380 creator A5067961995 @default.
- W4285820380 creator A5085295776 @default.
- W4285820380 date "2022-01-01" @default.
- W4285820380 modified "2023-10-16" @default.
- W4285820380 title "Metabolomics applied to the discovery of new bioactive pharmaceuticals in complex matrices" @default.
- W4285820380 cites W1515608624 @default.
- W4285820380 cites W1875987752 @default.
- W4285820380 cites W1881210807 @default.
- W4285820380 cites W1914090123 @default.
- W4285820380 cites W1971804539 @default.
- W4285820380 cites W1973836335 @default.
- W4285820380 cites W1975237170 @default.
- W4285820380 cites W1984926446 @default.
- W4285820380 cites W1985166156 @default.
- W4285820380 cites W1986026232 @default.
- W4285820380 cites W1998408895 @default.
- W4285820380 cites W2000706716 @default.
- W4285820380 cites W2006682635 @default.
- W4285820380 cites W2013458793 @default.
- W4285820380 cites W2034094398 @default.
- W4285820380 cites W2052235634 @default.
- W4285820380 cites W2052932116 @default.
- W4285820380 cites W2054715966 @default.
- W4285820380 cites W2090727031 @default.
- W4285820380 cites W2093486135 @default.
- W4285820380 cites W2094356685 @default.
- W4285820380 cites W2095762159 @default.
- W4285820380 cites W2105435654 @default.
- W4285820380 cites W2109770073 @default.
- W4285820380 cites W2121608529 @default.
- W4285820380 cites W2122407945 @default.
- W4285820380 cites W2123142851 @default.
- W4285820380 cites W2131059095 @default.
- W4285820380 cites W2138838392 @default.
- W4285820380 cites W2144169294 @default.
- W4285820380 cites W2145323393 @default.
- W4285820380 cites W2149617981 @default.
- W4285820380 cites W2156797025 @default.
- W4285820380 cites W2158827997 @default.
- W4285820380 cites W2162539049 @default.
- W4285820380 cites W2191444 @default.
- W4285820380 cites W2224175912 @default.
- W4285820380 cites W2236898154 @default.
- W4285820380 cites W2266905719 @default.
- W4285820380 cites W2293537897 @default.
- W4285820380 cites W2313946855 @default.
- W4285820380 cites W2313963825 @default.
- W4285820380 cites W2319777973 @default.
- W4285820380 cites W2336267598 @default.
- W4285820380 cites W2464798864 @default.
- W4285820380 cites W2467820898 @default.
- W4285820380 cites W2497111153 @default.
- W4285820380 cites W2508709614 @default.
- W4285820380 cites W2520355680 @default.
- W4285820380 cites W2524578434 @default.
- W4285820380 cites W2539166394 @default.
- W4285820380 cites W2543102381 @default.
- W4285820380 cites W2559063560 @default.
- W4285820380 cites W2559471922 @default.
- W4285820380 cites W2580321716 @default.
- W4285820380 cites W2580506960 @default.
- W4285820380 cites W2591952929 @default.
- W4285820380 cites W2616759956 @default.
- W4285820380 cites W2624683722 @default.
- W4285820380 cites W2625397981 @default.
- W4285820380 cites W2728621008 @default.
- W4285820380 cites W2737075235 @default.
- W4285820380 cites W2743576058 @default.
- W4285820380 cites W2748699441 @default.
- W4285820380 cites W2752811900 @default.
- W4285820380 cites W2756531013 @default.
- W4285820380 cites W2766555197 @default.
- W4285820380 cites W2766938499 @default.
- W4285820380 cites W2769418630 @default.
- W4285820380 cites W2797100077 @default.
- W4285820380 cites W2802667260 @default.
- W4285820380 cites W2805936801 @default.
- W4285820380 cites W2807305253 @default.
- W4285820380 cites W2808965743 @default.
- W4285820380 cites W2883909933 @default.
- W4285820380 cites W2886413283 @default.
- W4285820380 cites W2886927019 @default.
- W4285820380 cites W2889048143 @default.
- W4285820380 cites W2892182939 @default.
- W4285820380 cites W2894548295 @default.
- W4285820380 cites W2899689487 @default.
- W4285820380 cites W2899836869 @default.
- W4285820380 cites W2900512735 @default.
- W4285820380 cites W2900682826 @default.
- W4285820380 cites W2904492624 @default.
- W4285820380 cites W2910285616 @default.
- W4285820380 cites W2912696553 @default.
- W4285820380 cites W2914466708 @default.