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- W4286207832 abstract "Two new chlorinated guaianane-type sesquiterpenes (named chlosigesolides A and B) together with eight known compounds were isolated from the leaves and twigs of Sigesbeckia orientalis. Their structures were determined by analysis of HR-ESI-MS, 1D- and 2D-NMR spectral data as well as comparison with the literature. Absolute configurations of new compounds were elucidated by NOESY and ECD methods. Chlosigesolide A inhibited NO production in LPS-stimulated RAW264.7 macrophages with IC50 value of 10.9 ± 0.8 μM. Other compounds exhibited inhibitory activity at IC50 in range of 26.5 to 49.7 μM." @default.
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- W4286207832 date "2022-07-21" @default.
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- W4286207832 title "Two new chlorinated sesquiterpenes from <i>Sigesbeckia orientalis</i>" @default.
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- W4286207832 doi "https://doi.org/10.1080/14786419.2022.2099389" @default.
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