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• W4286222832 endingPage "4398" @default.
• W4286222832 startingPage "4398" @default.
• W4286222832 abstract "Full-ring dual-modal ultrasound and photoacoustic imaging provide complementary contrasts, high spatial resolution, full view angle and are more desirable in pre-clinical and clinical applications. However, two long-standing challenges exist in achieving high-quality video-rate dual-modal imaging. One is the increased data processing burden from the dense acquisition. Another one is the object-dependent speed of sound variation, which may cause blurry, splitting artifacts, and low imaging contrast. Here, we develop a video-rate full-ring ultrasound and photoacoustic computed tomography (VF-USPACT) with real-time optimization of the speed of sound. We improve the imaging speed by selective and parallel image reconstruction. We determine the optimal sound speed via co-registered ultrasound imaging. Equipped with a 256-channel ultrasound array, the dual-modal system can optimize the sound speed and reconstruct dual-modal images at 10 Hz in real-time. The optimized sound speed can effectively enhance the imaging quality under various sample sizes, types, or physiological states. In animal and human imaging, the system shows co-registered dual contrasts, high spatial resolution (140 µm), single-pulse photoacoustic imaging (< 50 µs), deep penetration (> 20 mm), full view, and adaptive sound speed correction. We believe VF-USPACT can advance many real-time biomedical imaging applications, such as vascular disease diagnosing, cancer screening, or neuroimaging." @default.
• W4286222832 created "2022-07-21" @default.
• W4286222832 creator A5033155840 @default.
• W4286222832 creator A5078864574 @default.
• W4286222832 date "2022-07-27" @default.
• W4286222832 modified "2023-10-14" @default.
• W4286222832 title "Video-rate full-ring ultrasound and photoacoustic computed tomography with real-time sound speed optimization" @default.
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• W4286222832 doi "https://doi.org/10.1364/boe.464360" @default.
• W4286222832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36032563" @default.
• W4286222832 hasPublicationYear "2022" @default.
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