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• W4286250210 startingPage "109418" @default.
• W4286250210 abstract "Low birth weight (LBW), as a major concern in public health, is now increasing worldwide, but its main indoor environmental factors remain unclear. We examined whether LBW including term-LBW (T-LBW) and preterm-LBW (P-LBW) was associated with maternal exposure to indoor environmental factors, with a purpose to identify the key indoor environmental factor(s) contributing to LBW. A nationwide retrospective cohort study of 30,735 pre-schoolers in six Chinese cities was performed from 2010 to 2012. One questionnaire survey was conducted to collect information on the pre-schoolers’ birth outcomes and their maternal exposure of indoor environmental factors including new furniture, house redecoration, cooking fuels, mould/damp stains, and mouldy odour during pregnancy. Maternal exposure of traffic-related air pollutant (NO2), industrial pollutant (SO2), and inhalable particulate matter (PM10), as well as meteorological parameters, was estimated in pregnancy. Associations of LBW, T-LBW and P-LBW with indoor environmental factors were evaluated by two-level (city-child) logistic regression models with an odds ratio (OR) and 95% confidence interval (CI). We found that P-LBW (1.0%) and T-LBW (1.4%) prevalence were respectively associated with persistent mould/damp stains and mouldy odour exposure in utero, ORs = 1.81 (95% CI: 1.01–3.24) and 1.49 (95% CI: 1.01–2.21). Exposure to high temperature and PM2.5 in pregnancy significantly enhanced the effect of persistent mould/damp stains and/or mouldy odour on P-LBW and LBW, ORs (95% CI) = 2.92 (1.40–6.07) and 1.78 (1.00–3.15) with significant interaction p values of 0.067 and 0.094 respectively. Sensitivity analysis suggested that raising cats and dogs significantly increased LBW risk of persistent mould/damp stains and mouldy odour exposure. Our findings indicate that long-term exposure to indoor mould/damp stains and mouldy odour in utero plays a key role in LBW, and this association can be significantly modified by some specific personal, indoor, and outdoor factors." @default.
• W4286250210 created "2022-07-21" @default.
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• W4286250210 date "2022-08-01" @default.
• W4286250210 modified "2023-10-15" @default.
• W4286250210 title "Long-term exposure to mould/damp stains and mouldy odour increases low birth weight" @default.
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• W4286250210 doi "https://doi.org/10.1016/j.buildenv.2022.109418" @default.
• W4286250210 hasPublicationYear "2022" @default.
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