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- W4286253384 abstract "Glomerular injury is the major cause of chronic kidney diseases (CKD) worldwide and is characterized by proteinuria. Glomerulonephritis (GN) has a wide spectrum of etiologies, the intensity of glomerular damage, histopathology, and clinical outcomes that can be associated with the landscape of the nephritogenic immune response. Beyond impaired immune responses and genetic factors, recent evidence indicates that microbiota can be contributed to the pathogenesis of GN and patients' outcomes by impacting many aspects of the innate and adaptive immune systems. It is still unknown whether dysbiosis induces GN or it is a secondary effect of the disease. Several factors such as drugs and nutritional problems can lead to dysbiosis in GN patients. It has been postulated that gut dysbiosis activates immune responses, promotes a state of systemic inflammation, and produces uremic toxins contributing to kidney tissue inflammation, apoptosis, and subsequent proteinuric nephropathy. In this review, the impact of gastrointestinal tract (GI) microbiota on the pathogenesis of the primary GN will be highlighted. The application of therapeutic interventions based on the manipulation of gut microbiota with special diets and probiotic supplementation can be effective in GN." @default.
- W4286253384 created "2022-07-21" @default.
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- W4286253384 date "2022-12-01" @default.
- W4286253384 modified "2023-09-30" @default.
- W4286253384 title "Microbiota and glomerulonephritis: An immunological point of view" @default.
- W4286253384 cites W1905339949 @default.
- W4286253384 cites W1968105193 @default.
- W4286253384 cites W1968960234 @default.
- W4286253384 cites W1974365779 @default.
- W4286253384 cites W1974782442 @default.
- W4286253384 cites W1985244471 @default.
- W4286253384 cites W1986810728 @default.
- W4286253384 cites W1994885812 @default.
- W4286253384 cites W1999906527 @default.
- W4286253384 cites W2001870151 @default.
- W4286253384 cites W2011344217 @default.
- W4286253384 cites W2020772760 @default.
- W4286253384 cites W2028585463 @default.
- W4286253384 cites W2033023902 @default.
- W4286253384 cites W2037259928 @default.
- W4286253384 cites W2042673794 @default.
- W4286253384 cites W2049228689 @default.
- W4286253384 cites W2050395078 @default.
- W4286253384 cites W2055394761 @default.
- W4286253384 cites W2073103098 @default.
- W4286253384 cites W2075462403 @default.
- W4286253384 cites W2097896939 @default.
- W4286253384 cites W2100096695 @default.
- W4286253384 cites W2103133409 @default.
- W4286253384 cites W2103561589 @default.
- W4286253384 cites W2104975759 @default.
- W4286253384 cites W2106273653 @default.
- W4286253384 cites W2109489841 @default.
- W4286253384 cites W2111731663 @default.
- W4286253384 cites W2112724457 @default.
- W4286253384 cites W2118455790 @default.
- W4286253384 cites W2121189266 @default.
- W4286253384 cites W2137333865 @default.
- W4286253384 cites W2144080504 @default.
- W4286253384 cites W2145416218 @default.
- W4286253384 cites W2158873077 @default.
- W4286253384 cites W2162062989 @default.
- W4286253384 cites W2163802009 @default.
- W4286253384 cites W2166822765 @default.
- W4286253384 cites W2211069246 @default.
- W4286253384 cites W2252671813 @default.
- W4286253384 cites W2340407049 @default.
- W4286253384 cites W2464094283 @default.
- W4286253384 cites W2468863425 @default.
- W4286253384 cites W2477547149 @default.
- W4286253384 cites W2563176552 @default.
- W4286253384 cites W2600340746 @default.
- W4286253384 cites W2601732801 @default.
- W4286253384 cites W2604156122 @default.
- W4286253384 cites W2617979892 @default.
- W4286253384 cites W2735051210 @default.
- W4286253384 cites W2740293841 @default.
- W4286253384 cites W2792638616 @default.
- W4286253384 cites W2792856196 @default.
- W4286253384 cites W2802126353 @default.
- W4286253384 cites W2884180680 @default.
- W4286253384 cites W2898908893 @default.
- W4286253384 cites W2899782641 @default.
- W4286253384 cites W2900539112 @default.
- W4286253384 cites W2900796514 @default.
- W4286253384 cites W2902866635 @default.
- W4286253384 cites W2913800245 @default.
- W4286253384 cites W2923723307 @default.
- W4286253384 cites W2945863650 @default.
- W4286253384 cites W2964875932 @default.
- W4286253384 cites W2983196129 @default.
- W4286253384 cites W2991043099 @default.
- W4286253384 cites W3005844983 @default.
- W4286253384 cites W3012524903 @default.
- W4286253384 cites W3035852992 @default.
- W4286253384 cites W3037038749 @default.
- W4286253384 cites W3049159101 @default.
- W4286253384 cites W3089353015 @default.
- W4286253384 cites W3093578073 @default.
- W4286253384 cites W3093943929 @default.
- W4286253384 cites W3109932793 @default.
- W4286253384 cites W3112879429 @default.
- W4286253384 cites W3120932984 @default.
- W4286253384 cites W3129607964 @default.
- W4286253384 cites W4210445361 @default.
- W4286253384 cites W4211099860 @default.
- W4286253384 cites W4239292067 @default.
- W4286253384 doi "https://doi.org/10.1016/j.amjms.2022.05.025" @default.
- W4286253384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35870511" @default.