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• W4286374090 abstract "Cell–cell adhesion plays a key role in the assembly of individual cells into coherent and functional multicellular organisms. Structural and molecular studies have shed light on the mechanisms whereby diverse types of intercellular junctions support tissue morphogenesis and integration, and intercellular communication. Focusing on cadherin-based adherens junctions, we address the functional and molecular architecture of these adhesions, including the mechanism of cadherin–cadherin interactions, the role of the cytoplasmic plaque in junction formation and signaling, and the critical role of the cytoskeleton in tissue scaffolding. Finally, we discuss the challenge of understanding the complex, yet precise networking of adhesion-associated molecules during tissue integration and embryonic development." @default.
• W4286374090 created "2022-07-21" @default.
• W4286374090 creator A5048943966 @default.
• W4286374090 creator A5056940923 @default.
• W4286374090 creator A5065149752 @default.
• W4286374090 date "2023-01-01" @default.
• W4286374090 modified "2023-10-16" @default.
• W4286374090 title "The Molecular Architecture of Cadherin-Mediated Cell-Cell Adhesions" @default.
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