FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286382655> ?p ?o ?g. }

• W4286382655 abstract "Abstract Background Behavioural features of anorexia nervosa (AN) suggest abnormalities in reward and habit. Neuroimaging evidence suggests morphometric and functional perturbations within these circuits, although fewer studies have assessed white matter characteristics in AN, and no studies to date have assessed white matter microstructure in AN. Methods In this brain imaging study, 29 female adolescents with partially or fully weight-restored AN and 27 healthy controls, all between 10-19 years, underwent whole-brain multi-shell diffusion tensor imaging. Utilizing neurite orientation dispersion and density imaging methods, we investigated group differences in white matter neurite density, orientation dispersion, and myelin density in tracts between prominent nodes of the reward circuit (ventral tegmental area (VTA) to nucleus accumbens (NAcc)) and the habit circuit (sensory motor area (SMA) to putamen). Results Findings revealed reduced neurite (F=5.20, p=0.027) and myelin density (F=5.39, p=0.025) in the left VTA-NAcc tract, and reduced orientation dispersion in the left (F=7.00, p=0.011) and right (F=6.77, p=0.012) VTA-NAcc tract. There were no significant group differences in the SMA-putamen tract. Significant relationships, after corrections, were not evident between tract microstructure and reward responsiveness, compulsive behaviours, illness duration, or BMI. Conclusions Adolescents with AN exhibit less dense, undermyelinated, and less dispersed white matter tracts connecting prominent reward system nodes, which may signify underutilization of this part of the reward circuit. These results provide a detailed examination of white matter microstructure in tracts underlying instrumental behavioral phenotypes contributing to illness in AN." @default.
• W4286382655 created "2022-07-22" @default.
• W4286382655 creator A5003434650 @default.
• W4286382655 creator A5040702751 @default.
• W4286382655 creator A5050932653 @default.
• W4286382655 creator A5059936945 @default.
• W4286382655 creator A5065521176 @default.
• W4286382655 creator A5090118852 @default.
• W4286382655 date "2022-07-21" @default.
• W4286382655 modified "2023-10-18" @default.
• W4286382655 title "White Matter Microstructure in Habit and Reward Circuits in Anorexia Nervosa: Insights from a Neurite Orientation Dispersion and Density Imaging Study" @default.
• W4286382655 cites W1598274867 @default.
• W4286382655 cites W1759119821 @default.
• W4286382655 cites W1899329334 @default.
• W4286382655 cites W1899759537 @default.
• W4286382655 cites W1968853557 @default.
• W4286382655 cites W1970928383 @default.
• W4286382655 cites W1972115344 @default.
• W4286382655 cites W1978611788 @default.
• W4286382655 cites W1989485530 @default.
• W4286382655 cites W1998954528 @default.
• W4286382655 cites W2003136337 @default.
• W4286382655 cites W2006740326 @default.
• W4286382655 cites W2008475506 @default.
• W4286382655 cites W2032254014 @default.
• W4286382655 cites W2033809837 @default.
• W4286382655 cites W2042181481 @default.
• W4286382655 cites W2046878213 @default.
• W4286382655 cites W2056344892 @default.
• W4286382655 cites W2071881327 @default.
• W4286382655 cites W2078436067 @default.
• W4286382655 cites W2084681347 @default.
• W4286382655 cites W2088954667 @default.
• W4286382655 cites W2090073984 @default.
• W4286382655 cites W2098874330 @default.
• W4286382655 cites W2115944765 @default.
• W4286382655 cites W2127309075 @default.
• W4286382655 cites W2141335893 @default.
• W4286382655 cites W2150775406 @default.
• W4286382655 cites W2165137514 @default.
• W4286382655 cites W2171765721 @default.
• W4286382655 cites W2191069827 @default.
• W4286382655 cites W2206024306 @default.
• W4286382655 cites W2407490173 @default.
• W4286382655 cites W2412769982 @default.
• W4286382655 cites W2598321609 @default.
• W4286382655 cites W2599651071 @default.
• W4286382655 cites W2768923071 @default.
• W4286382655 cites W2883430979 @default.
• W4286382655 cites W2883484847 @default.
• W4286382655 cites W2893532472 @default.
• W4286382655 cites W2894385768 @default.
• W4286382655 cites W2898573027 @default.
• W4286382655 cites W2912447341 @default.
• W4286382655 cites W2937870564 @default.
• W4286382655 cites W2974430968 @default.
• W4286382655 cites W2977883299 @default.
• W4286382655 cites W2984787707 @default.
• W4286382655 cites W3160417957 @default.
• W4286382655 cites W3175484112 @default.
• W4286382655 cites W3188029660 @default.
• W4286382655 cites W3212083327 @default.
• W4286382655 cites W3214990766 @default.
• W4286382655 cites W4220746370 @default.
• W4286382655 cites W4241074797 @default.
• W4286382655 cites W4247665917 @default.
• W4286382655 cites W4253520917 @default.
• W4286382655 doi "https://doi.org/10.1101/2022.07.20.22277868" @default.
• W4286382655 hasPublicationYear "2022" @default.
• W4286382655 type Work @default.
• W4286382655 citedByCount "0" @default.
• W4286382655 crossrefType "posted-content" @default.
• W4286382655 hasAuthorship W4286382655A5003434650 @default.
• W4286382655 hasAuthorship W4286382655A5040702751 @default.
• W4286382655 hasAuthorship W4286382655A5050932653 @default.
• W4286382655 hasAuthorship W4286382655A5059936945 @default.
• W4286382655 hasAuthorship W4286382655A5065521176 @default.
• W4286382655 hasAuthorship W4286382655A5090118852 @default.
• W4286382655 hasBestOaLocation W42863826551 @default.
• W4286382655 hasConcept C113246987 @default.
• W4286382655 hasConcept C126838900 @default.
• W4286382655 hasConcept C143409427 @default.
• W4286382655 hasConcept C149550507 @default.
• W4286382655 hasConcept C15744967 @default.
• W4286382655 hasConcept C169760540 @default.
• W4286382655 hasConcept C202751555 @default.
• W4286382655 hasConcept C2779714222 @default.
• W4286382655 hasConcept C2781192897 @default.
• W4286382655 hasConcept C55493867 @default.
• W4286382655 hasConcept C58693492 @default.
• W4286382655 hasConcept C71924100 @default.
• W4286382655 hasConcept C86803240 @default.
• W4286382655 hasConceptScore W4286382655C113246987 @default.
• W4286382655 hasConceptScore W4286382655C126838900 @default.
• W4286382655 hasConceptScore W4286382655C143409427 @default.
• W4286382655 hasConceptScore W4286382655C149550507 @default.
• W4286382655 hasConceptScore W4286382655C15744967 @default.
• W4286382655 hasConceptScore W4286382655C169760540 @default.
• W4286382655 hasConceptScore W4286382655C202751555 @default.
• W4286382655 hasConceptScore W4286382655C2779714222 @default.

• next