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- W4286436745 abstract "Children with complex medical conditions pose many difficulties in the evaluation and prevention of their nephrolithiasis episodes. DeFoor et al. present the next logical step in understanding the etiology of urinary stone disease in these children. The authors investigated the 24-h urine analyses of children with complex chronic conditions, many of whom depend upon enteral nutrition, and compared these to an unmatched cohort of otherwise healthy children with nephrolithiasis. While such an analysis is limited due to the retrospective and uncontrolled nature of the assessments, the difficulty in obtaining urine samples in such a population makes this study a valuable manuscript for future reference. Interestingly, as opposed to common hypotheses related to calcium metabolism in the chronically immobilized, the authors found a significantly higher concentration of urinary oxalate in the study population. Several possibilities could exist to explain these differences. Oxalate is known to vary more substantially in younger populations and perhaps repeat 24-h studies would yield different results [ [1] Ellison J.S. Hollingsworth J.M. Langman C.B. Asplin J.R. Schwaderer A.L. Yan P. et al. Analyte variations in consecutive 24-hour urine collections in children. J Pediatr Urol. 2017; 13 (632 e1- e7) Google Scholar ]. However, supposing these findings represent true and meaningful differences in urinary oxalate, a consideration of oxalate metabolism is warranted. Enteral nutrition and the risk of nephrolithiasis in complex pediatric patientsJournal of Pediatric UrologyVol. 18Issue 6PreviewMedically complex, non-ambulatory children can often suffer from nephrolithiasis. The purpose of this study is to determine risk factors which are predictive for recurrent stone formation in this patient population. Full-Text PDF" @default.
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- W4286436745 date "2022-12-01" @default.
- W4286436745 modified "2023-10-16" @default.
- W4286436745 title "Enteral feeding programs and hyperoxaluria: Is there a missing link?" @default.
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- W4286436745 doi "https://doi.org/10.1016/j.jpurol.2022.06.025" @default.
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