Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286457090> ?p ?o ?g. }
- W4286457090 abstract "Automated infrared pupillometry (AIP) and the Neurological Pupil index (NPi) provide an objective means of assessing and trending the pupillary light reflex (PLR) across a broad spectrum of neurological diseases. NPi quantifies the PLR and ranges from 0 to 5; in healthy individuals, the NPi of both eyes is expected to be ≥ 3.0 and symmetric. AIP values demonstrate emerging value as a prognostic tool with predictive properties that could allow practitioners to anticipate neurological deterioration and recovery. The presence of an NPi differential (a difference ≥ 0.7 between the left and right eye) is a potential sign of neurological abnormality.We explored NPi differential by considering the modified Rankin Score at discharge (DC mRS) among patients admitted to neuroscience intensive care units (NSICU) of 4 U.S. and 1 Japanese hospitals and for two cohorts of brain injuries: stroke (including subarachnoid hemorrhage, intracerebral hemorrhage, acute ischemic stroke, and aneurysm, 1,200 total patients) and 185 traumatic brain injury (TBI) patients for a total of more than 54,000 pupillary measurements.Stroke patients with at least 1 occurrence of an NPi differential during their NSICU stay have higher DC mRS scores (3.9) compared to those without an NPi differential (2.7; P < .001). Patients with TBI and at least 1 occurrence of an NPi differential during their NSICU stay have higher discharge modified Rankin Scale scores (4.1) compared to those without an NPi differential (2.9; P < .001). When patients experience both abnormalities, abnormal (NPi < 3.0) and an NPi differential, the latter has an anticipatory relationship with respect to the former (P < .001 for z-score skewness analysis). Finally, our analysis confirmed ≥ 0.7 as the optimal cutoff value for the NPi differential (AUC = 0.71, P < .001).The NPi differential is an important factor that clinicians should consider when managing critically ill neurological injured patients admitted to the neurocritical care units.NCT02804438 , Date of Registration: June 17, 2016." @default.
- W4286457090 created "2022-07-22" @default.
- W4286457090 creator A5000119772 @default.
- W4286457090 creator A5012265446 @default.
- W4286457090 creator A5012372014 @default.
- W4286457090 creator A5012736325 @default.
- W4286457090 creator A5014142767 @default.
- W4286457090 creator A5015193966 @default.
- W4286457090 creator A5022235353 @default.
- W4286457090 creator A5027936412 @default.
- W4286457090 creator A5045534541 @default.
- W4286457090 creator A5056459555 @default.
- W4286457090 creator A5058107374 @default.
- W4286457090 creator A5060039279 @default.
- W4286457090 creator A5067623584 @default.
- W4286457090 creator A5081391616 @default.
- W4286457090 creator A5086645960 @default.
- W4286457090 creator A5090397147 @default.
- W4286457090 date "2022-07-22" @default.
- W4286457090 modified "2023-10-14" @default.
- W4286457090 title "A differential of the left eye and right eye neurological pupil index is associated with discharge modified Rankin scores in neurologically injured patients" @default.
- W4286457090 cites W1833183833 @default.
- W4286457090 cites W1967657577 @default.
- W4286457090 cites W1971495995 @default.
- W4286457090 cites W1977326598 @default.
- W4286457090 cites W2000258118 @default.
- W4286457090 cites W2013356568 @default.
- W4286457090 cites W2020074777 @default.
- W4286457090 cites W2022267772 @default.
- W4286457090 cites W2028402931 @default.
- W4286457090 cites W2042762244 @default.
- W4286457090 cites W2075222938 @default.
- W4286457090 cites W2139540288 @default.
- W4286457090 cites W2144513042 @default.
- W4286457090 cites W2145131109 @default.
- W4286457090 cites W2209910959 @default.
- W4286457090 cites W2475217202 @default.
- W4286457090 cites W2511758608 @default.
- W4286457090 cites W2522738478 @default.
- W4286457090 cites W2556696393 @default.
- W4286457090 cites W2586915389 @default.
- W4286457090 cites W2617595617 @default.
- W4286457090 cites W2625474800 @default.
- W4286457090 cites W2728132057 @default.
- W4286457090 cites W2760460727 @default.
- W4286457090 cites W2793982183 @default.
- W4286457090 cites W2897665238 @default.
- W4286457090 cites W2902796756 @default.
- W4286457090 cites W2902907967 @default.
- W4286457090 cites W2913945743 @default.
- W4286457090 cites W2925619144 @default.
- W4286457090 cites W2944686065 @default.
- W4286457090 cites W2953090918 @default.
- W4286457090 cites W2964005803 @default.
- W4286457090 cites W2969657719 @default.
- W4286457090 cites W2971538632 @default.
- W4286457090 cites W2980301746 @default.
- W4286457090 cites W2986459369 @default.
- W4286457090 cites W2996449624 @default.
- W4286457090 cites W3007026116 @default.
- W4286457090 cites W3008043626 @default.
- W4286457090 cites W3011221082 @default.
- W4286457090 cites W3034333924 @default.
- W4286457090 cites W3035486948 @default.
- W4286457090 cites W3085697581 @default.
- W4286457090 cites W3090515195 @default.
- W4286457090 cites W3094494803 @default.
- W4286457090 cites W3102943080 @default.
- W4286457090 cites W3174778717 @default.
- W4286457090 cites W3179526235 @default.
- W4286457090 cites W3210462046 @default.
- W4286457090 cites W4139711 @default.
- W4286457090 cites W4205698737 @default.
- W4286457090 cites W4243155514 @default.
- W4286457090 cites W4366064791 @default.
- W4286457090 doi "https://doi.org/10.1186/s12883-022-02801-3" @default.
- W4286457090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35869429" @default.
- W4286457090 hasPublicationYear "2022" @default.
- W4286457090 type Work @default.
- W4286457090 citedByCount "4" @default.
- W4286457090 countsByYear W42864570902022 @default.
- W4286457090 countsByYear W42864570902023 @default.
- W4286457090 crossrefType "journal-article" @default.
- W4286457090 hasAuthorship W4286457090A5000119772 @default.
- W4286457090 hasAuthorship W4286457090A5012265446 @default.
- W4286457090 hasAuthorship W4286457090A5012372014 @default.
- W4286457090 hasAuthorship W4286457090A5012736325 @default.
- W4286457090 hasAuthorship W4286457090A5014142767 @default.
- W4286457090 hasAuthorship W4286457090A5015193966 @default.
- W4286457090 hasAuthorship W4286457090A5022235353 @default.
- W4286457090 hasAuthorship W4286457090A5027936412 @default.
- W4286457090 hasAuthorship W4286457090A5045534541 @default.
- W4286457090 hasAuthorship W4286457090A5056459555 @default.
- W4286457090 hasAuthorship W4286457090A5058107374 @default.
- W4286457090 hasAuthorship W4286457090A5060039279 @default.
- W4286457090 hasAuthorship W4286457090A5067623584 @default.
- W4286457090 hasAuthorship W4286457090A5081391616 @default.
- W4286457090 hasAuthorship W4286457090A5086645960 @default.
- W4286457090 hasAuthorship W4286457090A5090397147 @default.
- W4286457090 hasBestOaLocation W42864570901 @default.