Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286493090> ?p ?o ?g. }
- W4286493090 endingPage "55" @default.
- W4286493090 startingPage "55" @default.
- W4286493090 abstract "Hyaline cartilage is an important tracheal structure, yet little is known about its molecular composition, complicating investigation of pathologies and replacement options. Our aim was to research tracheal hyaline cartilage structure, protective tissue factors and variations in healthy humans. The tissue material was obtained from 10 cadavers obtained from the Riga Stradins University Institute of Anatomy and Anthropology archive. Tissues were stained with Bismarck brown and PAS for glycosaminoglycans, and immunohistochemistry was performed for HBD-2, HBD-3, HBD-4, IL-10 and LL-37. The slides were inspected by light microscopy and Spearman’s rank correlation coefficient was calculated. The extracellular matrix was positive across hyaline cartilage for PAS, yet Bismarck brown marked positive proliferation and growth zones. Numerous positive cells for both factors were found in all zones. All of the antimicrobial defence molecules and cytokines were found in a moderate number of cells, except in the mature cell zone with few positive cells. Spearman’s rank correlation coefficient revealed strong and moderate correlations between studied factors. Hyaline cartilage is a tracheal defence structure with a moderate number of antimicrobial defence protein and cytokine immunoreactive cells as well as numerous glycosaminoglycan positive cells. The extracellular matrix glycosaminoglycans provide structural scaffolding and intercellular signalling. The correlations between the studied factors confirm the synergistic activity of them." @default.
- W4286493090 created "2022-07-22" @default.
- W4286493090 creator A5045630454 @default.
- W4286493090 creator A5049134143 @default.
- W4286493090 creator A5059095580 @default.
- W4286493090 date "2022-07-21" @default.
- W4286493090 modified "2023-10-18" @default.
- W4286493090 title "Glycosaminoglycan, Antimicrobial Defence Molecule and Cytokine Appearance in Tracheal Hyaline Cartilage of Healthy Humans" @default.
- W4286493090 cites W131947895 @default.
- W4286493090 cites W1550441131 @default.
- W4286493090 cites W1586925433 @default.
- W4286493090 cites W1596238579 @default.
- W4286493090 cites W1717865497 @default.
- W4286493090 cites W1799680372 @default.
- W4286493090 cites W1908251117 @default.
- W4286493090 cites W1951191421 @default.
- W4286493090 cites W1967069761 @default.
- W4286493090 cites W1968453074 @default.
- W4286493090 cites W1977555838 @default.
- W4286493090 cites W1991278091 @default.
- W4286493090 cites W1999059211 @default.
- W4286493090 cites W1999791329 @default.
- W4286493090 cites W2003528537 @default.
- W4286493090 cites W2005158748 @default.
- W4286493090 cites W2014695403 @default.
- W4286493090 cites W2014969421 @default.
- W4286493090 cites W2015611806 @default.
- W4286493090 cites W2044673580 @default.
- W4286493090 cites W2046648436 @default.
- W4286493090 cites W2054055118 @default.
- W4286493090 cites W2055003743 @default.
- W4286493090 cites W2056039068 @default.
- W4286493090 cites W2059942380 @default.
- W4286493090 cites W2060045921 @default.
- W4286493090 cites W2065361083 @default.
- W4286493090 cites W2067301372 @default.
- W4286493090 cites W2074889665 @default.
- W4286493090 cites W2075773623 @default.
- W4286493090 cites W2078639028 @default.
- W4286493090 cites W2078704061 @default.
- W4286493090 cites W2089624960 @default.
- W4286493090 cites W2089833177 @default.
- W4286493090 cites W2090042814 @default.
- W4286493090 cites W2094801500 @default.
- W4286493090 cites W2099708653 @default.
- W4286493090 cites W2108118904 @default.
- W4286493090 cites W2120244866 @default.
- W4286493090 cites W2129141151 @default.
- W4286493090 cites W2132399663 @default.
- W4286493090 cites W2148067829 @default.
- W4286493090 cites W2151801184 @default.
- W4286493090 cites W2159769639 @default.
- W4286493090 cites W2161673554 @default.
- W4286493090 cites W2166564704 @default.
- W4286493090 cites W2171027071 @default.
- W4286493090 cites W2172252610 @default.
- W4286493090 cites W2268945254 @default.
- W4286493090 cites W2289079759 @default.
- W4286493090 cites W2357232755 @default.
- W4286493090 cites W2410066345 @default.
- W4286493090 cites W2411864040 @default.
- W4286493090 cites W2415594186 @default.
- W4286493090 cites W2417826327 @default.
- W4286493090 cites W2529175214 @default.
- W4286493090 cites W2538429211 @default.
- W4286493090 cites W2546339689 @default.
- W4286493090 cites W2571621670 @default.
- W4286493090 cites W2587406388 @default.
- W4286493090 cites W2601068128 @default.
- W4286493090 cites W2748512066 @default.
- W4286493090 cites W2791977325 @default.
- W4286493090 cites W2969679316 @default.
- W4286493090 cites W3006889374 @default.
- W4286493090 cites W3008618577 @default.
- W4286493090 cites W3034980945 @default.
- W4286493090 cites W3080587041 @default.
- W4286493090 cites W308289310 @default.
- W4286493090 cites W3106609715 @default.
- W4286493090 cites W3115046804 @default.
- W4286493090 cites W3116770645 @default.
- W4286493090 cites W3160122268 @default.
- W4286493090 cites W3173959945 @default.
- W4286493090 cites W3196476261 @default.
- W4286493090 cites W3199698892 @default.
- W4286493090 cites W4205510731 @default.
- W4286493090 cites W4243234982 @default.
- W4286493090 doi "https://doi.org/10.3390/jfmk7030055" @default.
- W4286493090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35893329" @default.
- W4286493090 hasPublicationYear "2022" @default.
- W4286493090 type Work @default.
- W4286493090 citedByCount "0" @default.
- W4286493090 crossrefType "journal-article" @default.
- W4286493090 hasAuthorship W4286493090A5045630454 @default.
- W4286493090 hasAuthorship W4286493090A5049134143 @default.
- W4286493090 hasAuthorship W4286493090A5059095580 @default.
- W4286493090 hasBestOaLocation W42864930901 @default.
- W4286493090 hasConcept C105702510 @default.
- W4286493090 hasConcept C106487976 @default.